10 Best Allergy Mattress Covers 2025 in the United States

The SafeRest 100% Waterproof Mattress Protector is a solid option for those seeking a reliable shield against allergens and moisture. Its key strength lies in its complete waterproofing feature, which effectively guards against fluids like sweat and spills, ensuring your mattress stays clean and dry. This is particularly beneficial for individuals who might be sensitive to allergens, as it also acts as a barrier against dust mites and other unwanted creatures that may reside in your bedding. The breathable material promotes airflow, making it comfortable for sleep without causing overheating, and the quiet design ensures that you won’t be disturbed by crinkly noises during the night.

In terms of fit, this protector is designed to stretch and securely fit queen-size mattresses, which is a plus for maintaining a snug, wrinkle-free appearance. Cleaning is hassle-free, as it is machine washable, allowing you to easily maintain hygiene without much effort.

There are a few considerations to keep in mind. Although the protector is described as breathable, some users might still find it slightly warmer than standard cotton covers, especially in hotter climates. For those who prioritize cleanliness and allergen protection, particularly in settings like new homes or rental properties, this mattress protector is a smart choice. Just be aware of the potential for slight warmth during sleep, which may affect comfort for some users.

The Utopia Bedding Zippered Mattress Encasement Queen is designed to offer comprehensive protection for your mattress. Made from stretchable knitted polyester fabric, it provides a snug and comfortable fit for queen-sized mattresses with dimensions of 60 by 80 inches and a 15-inch deep pocket. One of its standout features is its 100% waterproof protection, thanks to the high-quality TPU backing, ensuring that any spills or leaks do not penetrate the mattress, keeping it clean and safe. Additionally, the encasement is bed bug and dust mite proof, offering peace of mind for those concerned with allergens and pests.

The zippered cover encloses the mattress entirely, creating a secure barrier from all sides. This encasement is also machine washable, making it easy to maintain, though users might need to tumble dry it afterward. However, while the polyester material is durable and protective, it may not be as breathable as other materials like cotton, potentially making it warmer to sleep on. The noise level is minimal, which is a plus for those who are light sleepers.

If you prioritize breathability over waterproofing, you might want to consider alternatives. This mattress encasement is best suited for those who need strong protection against spills, bed bugs, and dust mites, and who value easy maintenance.

The PlushDeluxe Premium Bamboo Mattress Protector is a strong contender in the allergy mattress cover category, particularly for those who prioritize comfort and protection. One of its key strengths is its hypoallergenic properties, making it ideal for allergy sufferers and anyone looking to reduce allergens in their sleeping environment. The use of natural bamboo fabric not only provides a soft feel but also promotes breathability, ensuring a cool and comfortable sleep. Its waterproof feature is impressive, effectively resisting fluids from spills or bodily accidents, which can be particularly beneficial for families with young children or pets.

In terms of fit, the protector is designed to accommodate a variety of mattress types and depths, going up to 18 inches, which adds versatility. Plus, it remains noiseless, a bonus for those who are sensitive to sounds while sleeping. The ease of cleaning is another highlight, as it's washable and maintains its quality over time.

Some potential drawbacks should be noted. While the bamboo material is generally durable, it may not be as robust as some synthetic options on the market, which could affect longevity. Additionally, although the protector is marketed as waterproof, it may not offer the same level of protection as thicker, more traditional waterproof covers. Lastly, while the white color looks clean, it may show stains more readily than darker options, potentially requiring more frequent washes to maintain its appearance.