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10 Best Anti Wrinkle Serums 2025 in the United States

From leading brands and best sellers available on the web.

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Obagi Medi

Obagi Medical

Obagi Medical ELASTIderm Facial Serum, 1.0 oz Pack of 2

#1

Winner

TruSkin Vi

TruSkin Naturals

TruSkin Vitamin C Serum – Anti Aging Facial Serum with Vitamin C, Hyaluronic Acid, Vitamin E & More – Brightening Serum for Dark Spots, Even Skin Tone, Eye Area, Fine Lines & Wrinkles, 1 Fl Oz

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Obagi Medi

Obagi Medical

Obagi Medical ELASTIderm Facial Serum, 1.0 oz Pack of 2

#2
SeoulCeuti

SeoulCeuticals

Editor’s Choice

SeoulCeuticals Korean Skin Care 20% Vitamin C Hyaluronic Acid Serum + CE Ferulic Acid - Potent Anti Aging, Anti Wrinkle Korean Beauty 1oz

#3
Vitamin C

Eclat Skincare

Vitamin C Face Serum - Dark Spot Remover Facial Serum, Vit C Serum with Hyaluronic Acid, Ferulic Acid, & Vit E - Anti Aging and Skin Brightening Serum, Pure Vitamin C Serum Skin Care

#4
CeraVe Ant

CeraVe

CeraVe Anti Aging Retinol Serum | Cream Serum for Smoothing Fine Lines and Skin Brightening | With Retinol, Hyaluronic Acid, Niacinamide, and Ceramides | 1 Ounce

#5
Grace & St

grace & stella

Editor’s Choice

Grace & Stella Hyaluronic Acid Serum for Face - 50ml, Anti-Aging Serum with Hydrating and Brightening Properties, Vegan and Paraben-Free

#6
Tree of Li

Tree of Life Beauty

Editor’s Choice

Tree of Life Facial Skin Care Set, Brightening, Firming, Hydrating, Dry Face, Dermatologist Tested - Trio Power Kit, Vitamin C, Retinol and Hyaluronic Acid, 3 count of 1 Fl Oz

#7
Premium 20

ELBBUB

Premium 20% 𝐯𝐢𝐭𝐚𝐦𝐢𝐧 𝐜 𝐬𝐞𝐫𝐮𝐦 - (2PACK) with Hyaluronic Acid, Retinol & Amino Acids - Boost Skin Collagen,Hydrate & Plump Skin, Anti Aging & Wrinkle Facial Serum

#8
L'Oreal Pa

L’Oréal Paris

L'Oreal Paris Revitalift 1.5% Pure Hyaluronic Acid Face Serum, Hydrate & Reduce Wrinkles, Fragrance Free 1 oz

#9
RoC Retino

RoC

RoC Retinol Correxion Anti-Aging Wrinkle Night Serum, Daily Line Smoothing Skin Care Treatment for Fine Lines, Post-Acne Scars, 30 Individual Capsules, Unscented, 0.35 Fl Oz

#10
Advanced C

Advanced Clinicals

Advanced Clinicals 6X Concentrate Peptides Serum For Face | Hydrating + Firming Anti Wrinkle Collagen Peptide Moisturizer Face Oil W/Vitamin E For Wrinkles, Puffiness, & Uneven Skin Tone, 1.75 Fl Oz

More products we considered

grace & stella Award Winning Hyaluronic Acid Serum (30 ml/1 fl oz) Hyaluronic Acid Serum for Face - Acido Hialuronico Face Serum for Women - Hydrating Serum Remove Fine Lines, Wrinkles - Anti Aging

grace & stella Award Winning Hyaluronic Acid Serum (30 ml/1 fl oz) Hyaluronic Acid Serum for Face - Acido Hialuronico Face Serum for Women - Hydrating Serum Remove Fine Lines, Wrinkles - Anti Aging

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Tree of Life Facial Skin Care Set, Brightening, Firming, Hydrating, Dry Face, Dermatologist Tested

Tree of Life Facial Skin Care Set, Brightening, Firming, Hydrating, Dry Face, Dermatologist Tested

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Glow Recipe Niacinamide Dew Drops Face Serum - Hydrating Korean Skincare & Illuminating Makeup Primer for Dewy, Glass Skin - Hyaluronic Acid Serum for Brightening, Plumping & Highlighting (15ml)

Glow Recipe Niacinamide Dew Drops Face Serum - Hydrating Korean Skincare & Illuminating Makeup Primer for Dewy, Glass Skin - Hyaluronic Acid Serum for Brightening, Plumping & Highlighting (15ml)

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Tree of Life Vitamin C Serum for Face - for Dry and Sensitive Skin, Dermatologist-Tested

Tree of Life Vitamin C Serum for Face - for Dry and Sensitive Skin, Dermatologist-Tested

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Pacifica Face Oil Serum - Flower Fix Bi-Phase Hydrating Skin Barrier - w/Hyaluronic Acid & Natural Botanical Ingredients - for Dry Sensitive Skin Vegan & Cruelty-Free Dermatologist Approved

Pacifica Face Oil Serum - Flower Fix Bi-Phase Hydrating Skin Barrier - w/Hyaluronic Acid & Natural Botanical Ingredients - for Dry Sensitive Skin Vegan & Cruelty-Free Dermatologist Approved

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Our technology thoroughly searches through the online shopping world, reviewing hundreds of sites. We then process and analyze this information, updating in real-time to bring you the latest top-rated products. This way, you always get the best and most current options available.

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