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10 Best Antihistamine Eye Drops 2025 in the United States

From leading brands and best sellers available on the web.
#1

Winner

Pataday On

Alcon

Pataday Once Daily Relief Extra Strength Relief 2.5ml, 2 Count(Pack of 1)

#2
Optase Dry

Optase

Optase Dry Eye Intense Drops - Preservative Free Eye Drops for Long Lasting Relief - Artificial Tears to Relieve Severe Dry Eye Symptoms - Multidose Bottle - Step 3 Hydrate - .33 fl oz, 300 Doses

#3
Pataday On

Alcon

Pataday Once Daily Relief Allergy Eye Drops by Alcon, for Eye Allergy Itch Relief, 2.5 ml (Pack of 2)

#4
Visine Red

Visine

Visine Red Eye Hydrating Comfort Redness Relief and Lubricant Eye Drops to Help Moisturize and Relieve Red Eyes Due to Minor Eye Irritations Fast, Tetrahydrozoline HCl, 0.5 fl. oz

#5
Opcon-A Al

Opcon-A

Opcon-A Allergy Eye Drops by Bausch + Lomb, for Itch and Redness Relief, Red and Itchy Eyes Antihistamine Eye Drop, Clinically Proven Treatment, 0.5 Fl Oz (Pack of 2)

#6
Zaditor An

Zaditor

Zaditor Antihistamine Eye Drops, 5-mL

#7
Alaway Ant

Alaway

Alaway Antihistamine Eye Drops, Allergy Relief from Itchy Eyes, Works in Minutes, Provides Relief for up to 12 Hours, Clinically Tested Prescription Strength Formula, 0.34 Fl Oz

#8
Pataday Tw

Alcon

Pataday Twice Daily Relief, 0.17 Fl Oz

#9
Naphcon-A

NAPHCON-A

Naphcon-A Eye Drops, 15-mL

#10
Visine All

Visine

Visine Allergy Eye Relief Multi-Action Antihistamine & Redness Reliever Eye Drops with Pheniramine Maleate & Naphazoline HCl, Eye Drop Treatment for Red, Itchy, Allergy Eyes, 0.5 fl. oz

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