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Antiseptic Creams

10 Best Antiseptic Creams 2025 in the United States

Name: Neosporin Original Antibiotic Ointment, 24-Hour Infection Prevention for Minor Wound, 1 oz
Brand: Neosporin
Price: 8.48 USD
Availability: InStock

From leading brands and best sellers available on the web.

Ora's Amazing Herbal, Hand Salve Cream for Men, Healing Ointment, Foot Balm, Calendula Cream, Salve, Comfrey Salve, All Purpose Salve, Cracked Heels, Cuticle Cream

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Winner

Neosporin

Neosporin Original Antibiotic Ointment, 24-Hour Infection Prevention for Minor Wound, 1 oz

9.9

score

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Ora's Amazing Herbal, Hand Salve Cream for Men, Healing Ointment, Foot Balm, Calendula Cream, Salve, Comfrey Salve, All Purpose Salve, Cracked Heels, Cuticle Cream

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neosporin

Neosporin Original Antibiotic Ointment, 24-Hour Infection Prevention for Minor Wound, .5 oz

9.8

score

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Neosporin

Neosporin + Maximum-Strength Pain Relief Dual Action Cream, First Aid Topical Antibiotic & Analgesic Cream for Wound Care of Minor Cuts, Scrapes & Burns, Polymyxin B & Pramoxine HCl, 1 oz

9.6

score

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Bactine

Editor’s Choice

Bactine MAX Antibiotic + Pain Relieving Ointment - Antibiotic Ointment with Lidocaine - Pain + Itch Relief for Minor Cuts & Scrapes & Burns - Lidocaine Numbing Cream - 0.5oz

9.4

score

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Betadine

Betadine Clear First Aid Spray, Max Strength Pain Relieving Antiseptic Cleansing Spray, No Stinging, Kills 99.9% of Germs*, Helps Prevent Infections, 6 oz

9.2

score

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Neosporin

Neosporin Original Ointment First Aid Antibiotic Treatment 3 Pack Value Pack

8.9

score

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Polysporin

Polysporin First Aid Topical Antibiotic Skin Ointment with Bacitracin Zinc & Polymyxin B Sulfate, for Infection Protection & Wound Care, Neomycin-Free, Travel Size, 0.5 oz

8.7

score

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Dermoplast

Dermoplast Kids Sting-Free First Aid Spray, Antiseptic & Analgesic Spray for Minor Cuts, Scrapes and Burns, 2 Ounce

8.4

score

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Brave Soldier

Brave Soldier Antiseptic Healing Ointment - Accelerate Wound Healing Ointment - Best Wound Healing Cream, Scab Healing, Wound Care, Burn Ointment & Skin Repair - for Burns Wounds & More 1 oz (28g)

8.2

score

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#10

BLDG ACTIVE

Active Skin Repair Kids First Aid Spray - Non-Toxic & Natural Antiseptic for Minor Cuts, Wounds, Scrapes, Rashes, Sunburns, and Other Irritations (3oz Spray)

7.9

score

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More products we considered

FemiClear for Itching & Tingling - All-Natural Intimate Relief, 0.5 Oz

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Ora's Amazing Herbal Calendula Salve, Calendula Cream, Drawing Salve, Calendula Ointment, Coconut Free Salve made with Organic Calendula and Licorice Root, 4 oz

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CUROXEN First Aid Antibiotic Ointment, 0.5oz | All-Natural & Organic Ingredients (0.5oz Vertical)

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CUROXEN Mouth Sore Relief, Made with All-Natural Ingredients Including Olive Oil, Calendula, Beeswax, Clove Essential Oil, and Cinnamon Oil, Gluten-Free - 0.42 oz

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Bactine MAX 4 oz. Pain Relieving Cleansing Liquid

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How do we rank products for you?

Our technology thoroughly searches through the online shopping world, reviewing hundreds of sites. We then process and analyze this information, updating in real-time to bring you the latest top-rated products. This way, you always get the best and most current options available.

10 Best Antiseptic Creams 2025 in the United States

Ora's Amazing Herbal, Hand Salve Cream for Men, Healing Ointment, Foot Balm, Calendula Cream, Salve, Comfrey Salve, All Purpose Salve, Cracked Heels, Cuticle Cream

Neosporin Original Antibiotic Ointment, 24-Hour Infection Prevention for Minor Wound, 1 oz

Ora's Amazing Herbal, Hand Salve Cream for Men, Healing Ointment, Foot Balm, Calendula Cream, Salve, Comfrey Salve, All Purpose Salve, Cracked Heels, Cuticle Cream

Neosporin Original Antibiotic Ointment, 24-Hour Infection Prevention for Minor Wound, .5 oz

Neosporin + Maximum-Strength Pain Relief Dual Action Cream, First Aid Topical Antibiotic & Analgesic Cream for Wound Care of Minor Cuts, Scrapes & Burns, Polymyxin B & Pramoxine HCl, 1 oz

Bactine MAX Antibiotic + Pain Relieving Ointment - Antibiotic Ointment with Lidocaine - Pain + Itch Relief for Minor Cuts & Scrapes & Burns - Lidocaine Numbing Cream - 0.5oz

Betadine Clear First Aid Spray, Max Strength Pain Relieving Antiseptic Cleansing Spray, No Stinging, Kills 99.9% of Germs*, Helps Prevent Infections, 6 oz

Neosporin Original Ointment First Aid Antibiotic Treatment 3 Pack Value Pack

Polysporin First Aid Topical Antibiotic Skin Ointment with Bacitracin Zinc & Polymyxin B Sulfate, for Infection Protection & Wound Care, Neomycin-Free, Travel Size, 0.5 oz

Dermoplast Kids Sting-Free First Aid Spray, Antiseptic & Analgesic Spray for Minor Cuts, Scrapes and Burns, 2 Ounce

Brave Soldier Antiseptic Healing Ointment - Accelerate Wound Healing Ointment - Best Wound Healing Cream, Scab Healing, Wound Care, Burn Ointment & Skin Repair - for Burns Wounds & More 1 oz (28g)

Active Skin Repair Kids First Aid Spray - Non-Toxic & Natural Antiseptic for Minor Cuts, Wounds, Scrapes, Rashes, Sunburns, and Other Irritations (3oz Spray)

FemiClear for Itching & Tingling - All-Natural Intimate Relief, 0.5 Oz

Ora's Amazing Herbal Calendula Salve, Calendula Cream, Drawing Salve, Calendula Ointment, Coconut Free Salve made with Organic Calendula and Licorice Root, 4 oz

CUROXEN First Aid Antibiotic Ointment, 0.5oz | All-Natural & Organic Ingredients (0.5oz Vertical)

CUROXEN Mouth Sore Relief, Made with All-Natural Ingredients Including Olive Oil, Calendula, Beeswax, Clove Essential Oil, and Cinnamon Oil, Gluten-Free - 0.42 oz

Bactine MAX 4 oz. Pain Relieving Cleansing Liquid

FAQ

What are the best antiseptic creams available on the market?

How do antiseptic creams work?

Are antiseptic creams safe for children?

Can I use antiseptic cream on an open wound?

How often should I apply antiseptic cream to a wound?

10 Best Antiseptic Creams 2025 in the United States

Ora's Amazing Herbal, Hand Salve Cream for Men, Healing Ointment, Foot Balm, Calendula Cream, Salve, Comfrey Salve, All Purpose Salve, Cracked Heels, Cuticle Cream

Neosporin Original Antibiotic Ointment, 24-Hour Infection Prevention for Minor Wound, 1 oz

Ora's Amazing Herbal, Hand Salve Cream for Men, Healing Ointment, Foot Balm, Calendula Cream, Salve, Comfrey Salve, All Purpose Salve, Cracked Heels, Cuticle Cream

Neosporin Original Antibiotic Ointment, 24-Hour Infection Prevention for Minor Wound, .5 oz

Neosporin + Maximum-Strength Pain Relief Dual Action Cream, First Aid Topical Antibiotic & Analgesic Cream for Wound Care of Minor Cuts, Scrapes & Burns, Polymyxin B & Pramoxine HCl, 1 oz

Bactine MAX Antibiotic + Pain Relieving Ointment - Antibiotic Ointment with Lidocaine - Pain + Itch Relief for Minor Cuts & Scrapes & Burns - Lidocaine Numbing Cream - 0.5oz

Betadine Clear First Aid Spray, Max Strength Pain Relieving Antiseptic Cleansing Spray, No Stinging, Kills 99.9% of Germs*, Helps Prevent Infections, 6 oz

HClear for him by FemiClear - Topical Ointment - Formulated with All-Natural and Organic Ingredients - Fast-Acting Relief - Manufactured in The USA - (0.5 Oz Tube)

Bactine Max 5 oz Pain Relieving Spray 2 pk

Bactine MAX Antibiotic + Pain Relieving Ointment - Antibiotic Ointment with Lidocaine - Pain + Itch Relief for Minor Cuts & Scrapes & Burns - Lidocaine Numbing Cream - 0.5oz

Bactine MAX First Aid Spray - Pain Relief Cleansing Spray with 4% Lidocaine - Numbing Lidocaine Kills 99% of Germs - Pain + Itch Relief for Minor Cuts & Scrapes, Burns & Bug Bites - 5oz, 4 Pack

A+D First Aid Ointment, Multipurpose Dry Skin Moisturizer and Skin Protectant, 1.5 Oz (Pack of 3)

Neosporin Original Ointment First Aid Antibiotic Treatment 3 Pack Value Pack

Polysporin First Aid Topical Antibiotic Skin Ointment with Bacitracin Zinc & Polymyxin B Sulfate, for Infection Protection & Wound Care, Neomycin-Free, Travel Size, 0.5 oz

Dermoplast Kids Sting-Free First Aid Spray, Antiseptic & Analgesic Spray for Minor Cuts, Scrapes and Burns, 2 Ounce

Brave Soldier Antiseptic Healing Ointment - Accelerate Wound Healing Ointment - Best Wound Healing Cream, Scab Healing, Wound Care, Burn Ointment & Skin Repair - for Burns Wounds & More 1 oz (28g)

Active Skin Repair Kids First Aid Spray - Non-Toxic & Natural Antiseptic for Minor Cuts, Wounds, Scrapes, Rashes, Sunburns, and Other Irritations (3oz Spray)

Antiage Creams

Anticellulite Creams

Anti Aging Creams

Anti Itch Creams

Antiaging Creams

FemiClear for Itching & Tingling - All-Natural Intimate Relief, 0.5 Oz

Ora's Amazing Herbal Calendula Salve, Calendula Cream, Drawing Salve, Calendula Ointment, Coconut Free Salve made with Organic Calendula and Licorice Root, 4 oz

CUROXEN First Aid Antibiotic Ointment, 0.5oz | All-Natural & Organic Ingredients (0.5oz Vertical)

CUROXEN Mouth Sore Relief, Made with All-Natural Ingredients Including Olive Oil, Calendula, Beeswax, Clove Essential Oil, and Cinnamon Oil, Gluten-Free - 0.42 oz

Bactine MAX 4 oz. Pain Relieving Cleansing Liquid

FAQ

What are the best antiseptic creams available on the market?

How do antiseptic creams work?

Are antiseptic creams safe for children?

Can I use antiseptic cream on an open wound?

How often should I apply antiseptic cream to a wound?