10 Best Bed Bug Sprays 2025 in the United States

The Hot Shot Ready-to-Use Bed Bug Killer Spray is a versatile option designed to tackle bed bugs, bed bug eggs, fleas, and dust mites. Its water-based formula is beneficial as it is non-staining and leaves no odor, making it more pleasant for indoor use without worrying about lingering smells or marks. This spray is easy to use for spot treatments on mattresses, ensuring that all crucial areas are covered without the need for extensive spraying, although it should not be used on pets.

The 32-ounce volume provides ample product for multiple applications, which is necessary since the instructions recommend reapplication every two weeks as part of a comprehensive treatment plan. Users need to be diligent with this reapplication schedule to maintain control over an infestation, which could be seen as a drawback for those looking for a one-time solution.

Despite this, its targeted spray form and odorless nature make it a user-friendly option for those dealing with bed bugs and related pests inside the home. It is particularly effective when used as part of a broader pest control strategy.

The Hot Shot Bed Bug Killer Aerosol is designed to tackle bed bugs, bed bug eggs, and a variety of other crawling insects including fleas, ticks, dust mites, and carpet beetles. Its versatility allows it to be used on multiple surfaces such as mattresses, wood furniture, carpets, bed frames, headboards, floors, moldings, ceilings, and walls. This makes it a comprehensive solution for pest control.

The product claims to control bed bugs for up to 3 weeks on carpeted surfaces, providing a decent duration of effectiveness. Moreover, it boasts a non-staining formula with no unpleasant odor, which could make it more convenient for indoor use, especially in bedrooms and living areas. On the safety front, while it is meant for use on various household surfaces, users should handle the aerosol with care and follow the instructions to avoid any adverse effects.

The spray form can be straightforward to use, but coverage might require repeated applications for larger infestations. At 17.5 fluid ounces, the volume is manageable for handling but may not be sufficient for extensive treatments, requiring multiple cans for bigger areas. Being a specific solution for bed bugs and other insects, this product is well-suited for those who are facing multi-insect infestations in their living spaces and need an easy-to-use, low-odor, and non-staining solution.

The Ortho Home Defense Max Bed Bug, Flea and Tick Killer is a versatile 1-gallon spray designed to tackle bed bugs, including their eggs, as well as fleas and ticks. One of its strong points is its effectiveness against even the toughest bed bugs, including those resistant to common treatments. The Comfort Wand that comes with it makes it easier to apply, especially in hard-to-reach places such as mattress seams and baseboards. This feature can be a significant advantage for those dealing with infestations in multiple areas of their home.

Safety-wise, it should be used with care, keeping in mind the advice to use it as a spot treatment. It’s also important to note that while it is effective, it forms only one part of a three-step treatment system recommended by Ortho, which may require additional purchases for the best results. Users have generally rated it positively, with a 4.4 out of 5-star rating from nearly 29,000 reviews, indicating a high level of customer satisfaction. However, some users might find the scent unpleasant as it is noted to have a tick scent.

In terms of convenience, the product’s large volume (1 gallon) means you’ll have plenty of spray to cover a significant area, but it also makes the container heavier and potentially more cumbersome to handle. This product is well-suited for those looking for a comprehensive, albeit multi-step, solution to bed bug and flea infestations in their home.