10 Best Calming Products For Cats 2025 in the United States

The FELIWAY MultiCat Calming Pheromone, 30 Day Refill, is a pheromone product designed to reduce tension and conflict between cats. It mimics a mother cat’s natural pheromones, which can help to soothe and comfort multiple cats living in the same household. This product is drug-free and non-sedating, making it a safe choice for both cats and humans. Safety is further assured as it does not affect other pets in the home.

The product is easy to use; simply plug the diffuser into an open outlet, and it will continuously release the calming pheromone for up to 30 days. However, to maintain effectiveness, the vial needs to be replaced monthly, and the diffuser every six months. This could be seen as a recurring cost and minor inconvenience for some users. The product is backed by scientific research and 25 years of expertise, with 84% of cat owners reporting a significant improvement in cat conflicts.

The compact dimensions (1.75 x 1.75 x 3.25 inches) make it a discreet addition to the home. One limitation is that it requires a specific FELIWAY diffuser, so compatibility with other brands is not an option. It is an excellent product for cat owners seeking a non-invasive and scientifically supported method to reduce tensions between their pets.

The FELIWAY Optimum Enhanced Calming Pheromone is a 30-day refill designed to reduce stress-related behaviors in cats, such as scratching, urine spraying, and excessive hiding. As a non-sedating and drug-free solution, it releases pheromone analogs to provide a natural, reassuring message to cats, helping them feel more at ease. This product is easy to use—simply plug the diffuser into an open outlet with good air circulation, and it will work continuously for up to 30 days.

It’s important to use the FELIWAY diffuser with its specific refills for optimal results. One diffuser covers up to 700 square feet, and it should be replaced every six months, with refills changed monthly. Backed by over 25 years of research and recommended by vets, it’s a reliable choice for many cat owners.

However, it may not be universally effective for all cats, and the need to replace refills and diffusers regularly could be a recurring cost. Additionally, while it is safe for cats, humans, and other pets, it carries a specific scent (Mimosa) that may not appeal to everyone. This product is most beneficial for cat owners dealing with noticeable signs of feline stress in their homes.

The Purina Pro Plan Veterinary Supplements Calming Care Cat Supplements are well-regarded, with the brand being the number one veterinarian-recommended cat probiotic. This product uses a proprietary probiotic strain (BL999) designed to help manage stress and anxious behaviors in cats. It comes in a powder form with a liver flavor, which might appeal to many cats, making it relatively easy to administer by mixing it with their food.

The product claims to support positive behaviors, like playing and seeking social contact, while also helping to manage stress-related hormones like cortisol and support a healthy immune system. Each box contains 30 packets, enough for a month's supply, as it is recommended to give one packet daily. However, it can take up to six weeks to notice the full effects of the supplement, which might require some patience from pet owners.

Safety precautions indicate that this supplement is for cats only and should be used under the supervision of a veterinarian, particularly because the safety for pregnant cats or those intended for breeding has not been established. This could be a good option for cats that are prone to anxiety or stress, but it might not be the best fit for owners looking for more immediate results or those with pregnant cats.