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Cold Sore Remedies

10 Best Cold Sore Remedies 2025 in the United States

Name: Zicam Cold Remedy Zinc Rapidmelts, Citrus Flavor, 25 Count (Pack of 1)
Brand: Zicam
Price: 8.78 USD
Availability: InStock

From leading brands and best sellers available on the web.

Kids Cold Medicine for Ages 2+, Hyland's Naturals Kids Cold & Cough, Day and Night Value Pack, Grape Syrup, Cough Medicine for Kids, 4 Fl Oz Each, 2 Count (Pack of 1)

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Winner

Zicam

Zicam Cold Remedy Zinc Rapidmelts, Citrus Flavor, 25 Count (Pack of 1)

9.9

score

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Kids Cold Medicine for Ages 2+, Hyland's Naturals Kids Cold & Cough, Day and Night Value Pack, Grape Syrup, Cough Medicine for Kids, 4 Fl Oz Each, 2 Count (Pack of 1)

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Zicam

Zicam Cold Remedy Cold Shortening Medicated Nasal Swabs Zinc-Free 20ct

9.8

score

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Quantum Health

Quantum Health Super Lysine+ / Advanced Formula Lysine+ Immune Support with Vitamin C, Echinacea, Licorice, Propolis, Odorless Garlic (180 Tablets), Packaging may vary

9.7

score

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Mederma

Mederma Fever Blister Discreet Healing Patch - A Patch That Protects and Conceals Cold Sores - 15 Count

9.5

score

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Boiron

Boiron ColdCalm Tablets for Relief of Common Cold Symptoms Such as Sneezing, Runny Nose, Sore Throat, and Nasal Congestion - Non-Drowsy - 60 Count

9.3

score

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Abreva

Abreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Tube x 2

9.1

score

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Burt's Bees

Burt's Bees Stocking Stuffers, Cold Sore Treatment Bundle with Burt’s Bees Cold Sore Healing Patches and Cold Sore Treatment with Rhubarb and Sage, Protects and Heals Cold Sores, Relieves Symptoms

8.9

score

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Abreva

Abreva Cold Sore Treatment Rapid Pain Relief Cream - 1 Tube, 3 Grams

8.7

score

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Quantum

Quantum Health Lip Clear Lysine+ Cold Sore Treatment Soothe & Moisturize Mouth Sores - L-Lysine Menthol Calendula & Propolis Ointment - Transparent Fever Blister Healing Balm - 0.25 Oz

8.4

score

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#10

Clear Probiotics

Editor’s Choice

Cold Sore Treatment for Lips - Lysine Supercharged with Acidophilus Probiotic & Lactobacillus Rhamnosus + Vitamin C for Lip and Skin Health - Immune Support for Effective Prevention and Clear Skin

8.2

score

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More products we considered

HealthA2Z® Daytime and Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (24 Daytime & 12 Nighttime Softgels) (Daytime & Nighttime Combo (36 Count Pack of 1))

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Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

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HealthA2Z® Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (20 Softgels) (20 Softgels)

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HealthA2Z® Daytime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime(20 Softgels) (Daytime Cold & Flu Medicine (20 Count Pack of 1))

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HealthA2Z® Mucus Relief | Guaifenesin 600 mg | 12 Hour | No Benzene | Expectorant | Relieves Chest Congestion | Thins and Loosens Mucus | Extended Release (150 Counts)

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How do we rank products for you?

Our technology thoroughly searches through the online shopping world, reviewing hundreds of sites. We then process and analyze this information, updating in real-time to bring you the latest top-rated products. This way, you always get the best and most current options available.

10 Best Cold Sore Remedies 2025 in the United States

Kids Cold Medicine for Ages 2+, Hyland's Naturals Kids Cold & Cough, Day and Night Value Pack, Grape Syrup, Cough Medicine for Kids, 4 Fl Oz Each, 2 Count (Pack of 1)

Zicam Cold Remedy Zinc Rapidmelts, Citrus Flavor, 25 Count (Pack of 1)

Kids Cold Medicine for Ages 2+, Hyland's Naturals Kids Cold & Cough, Day and Night Value Pack, Grape Syrup, Cough Medicine for Kids, 4 Fl Oz Each, 2 Count (Pack of 1)

Zicam Cold Remedy Cold Shortening Medicated Nasal Swabs Zinc-Free 20ct

Quantum Health Super Lysine+ / Advanced Formula Lysine+ Immune Support with Vitamin C, Echinacea, Licorice, Propolis, Odorless Garlic (180 Tablets), Packaging may vary

Mederma Fever Blister Discreet Healing Patch - A Patch That Protects and Conceals Cold Sores - 15 Count

Boiron ColdCalm Tablets for Relief of Common Cold Symptoms Such as Sneezing, Runny Nose, Sore Throat, and Nasal Congestion - Non-Drowsy - 60 Count

Hyland's - Kids - Organic Cough & Immune Day & Night Combo Pack - Eases Coughs, Supports Immunity, Promotes Sleep, Two 4 Fl Oz. Bottles (8 fl oz) (Pack of 2)

Herbion Naturals Respiratory Care Herbal Granules – 10 Ct for The Whole Family – Promotes Healthy Nasal Passages & Respiratory Function - Relieves Cold and Flu Symptoms – Supports Immune System

HealthA2Z® Mucus Relief DM | Dextromethorphan HBr 20mg | Guaifenesin 400mg | No Benzene | Cough, Immediate Release, Uncoated (120 Count (Pack of 1))

HealthA2Z® Mucus Relief | Guaifenesin 400mg | Immediate Release | No Benzene | Expectorant (150 Counts)

HealthA2Z® Mucus Relief | Guaifenesin 1200 mg | NO Benzene |100 Tablets | Maximum Strength | 12 Hour | Expectorant | Relieves Chest Congestion | Thins and Loosens Mucus

Abreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Tube x 2

Burt's Bees Stocking Stuffers, Cold Sore Treatment Bundle with Burt’s Bees Cold Sore Healing Patches and Cold Sore Treatment with Rhubarb and Sage, Protects and Heals Cold Sores, Relieves Symptoms

Abreva Cold Sore Treatment Rapid Pain Relief Cream - 1 Tube, 3 Grams

Quantum Health Lip Clear Lysine+ Cold Sore Treatment Soothe & Moisturize Mouth Sores - L-Lysine Menthol Calendula & Propolis Ointment - Transparent Fever Blister Healing Balm - 0.25 Oz

Cold Sore Treatment for Lips - Lysine Supercharged with Acidophilus Probiotic & Lactobacillus Rhamnosus + Vitamin C for Lip and Skin Health - Immune Support for Effective Prevention and Clear Skin

Natural Cold Remedies

Little Remedies Cold Sore Remedies

Alka-Seltzer Cold Sore Remedies

Cold Remedies

HealthA2Z® Daytime and Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (24 Daytime & 12 Nighttime Softgels) (Daytime & Nighttime Combo (36 Count Pack of 1))

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

HealthA2Z® Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (20 Softgels) (20 Softgels)

HealthA2Z® Daytime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime(20 Softgels) (Daytime Cold & Flu Medicine (20 Count Pack of 1))

HealthA2Z® Mucus Relief | Guaifenesin 600 mg | 12 Hour | No Benzene | Expectorant | Relieves Chest Congestion | Thins and Loosens Mucus | Extended Release (150 Counts)