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Computer Mouse For Large Hands

10 Best Computer Mouse For Large Hands 2025 in the United States

Name: Amazon Basics Ergonomic 2.4 GHz Wireless Optical Mouse, DPI adjustable, Compatible with PC, Mac, Laptop - Black
Brand: Amazon Basics
Price: 11.31 USD
Availability: InStock

From leading brands and best sellers available on the web.

Logitech G305 LIGHTSPEED Wireless Gaming Mouse, Hero 12K Sensor, 12,000 DPI, Lightweight, 6 Programmable Buttons, 250h Battery Life, On-Board Memory, PC/Mac - Black

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Winner

Amazon Basics

Amazon Basics Ergonomic 2.4 GHz Wireless Optical Mouse, DPI adjustable, Compatible with PC, Mac, Laptop - Black

9.9

score

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Logitech G305 LIGHTSPEED Wireless Gaming Mouse, Hero 12K Sensor, 12,000 DPI, Lightweight, 6 Programmable Buttons, 250h Battery Life, On-Board Memory, PC/Mac - Black

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Redragon

Redragon M602 RGB Wired Gaming Mouse RGB Spectrum Backlit Ergonomic Mouse Griffin Programmable with 8 Backlight Modes, Up to 7200 DPI for Windows PC Gamers (Black)

9.8

score

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E-YOOSO

E-YOOSO Large Wireless Mouse, X-31 Large Mouse for Big Hands, 5-Level 4800 DPI, 6 Button Big Ergo Computer Mouse, 18 Months Battery Life Cordless Mouse for Laptop, Mac, Chromebook, PC, Windows(Black)

9.6

score

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Logitech

Logitech MX Master 3S - Wireless Performance Mouse, Ergo, 8K DPI, Track on Glass, Quiet Clicks, USB-C, Bluetooth, Windows, Linux, Chrome - Graphite - With Free Adobe Creative Cloud Subscription

9.3

score

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Logitech

Logitech MX Vertical Wireless Mouse – Ergonomic Design Reduces Muscle Strain, Move Content Between 3 Windows and Apple Computers, Rechargeable, Graphite

9.0

score

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Logitech

Logitech Lift Vertical Ergonomic Mouse, Wireless, Bluetooth or Logi Bolt USB receiver, Quiet clicks, 4 buttons, compatible with Windows/macOS/iPadOS, Laptop, PC - Graphite

8.7

score

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Logitech

Logitech ERGO M575 Wireless Trackball Mouse - Easy thumb control, precision and smooth tracking, ergonomic comfort design, for Windows, PC and Mac with Bluetooth and USB capabilities - Graphite

8.4

score

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Logitech

Logitech Signature M650 L Full Size Wireless Mouse - For Large Sized Hands, 2-Year Battery, Silent Clicks, Customizable Side Buttons, Bluetooth, for PC/Mac/Multi-Device/Chromebook - Black

8.1

score

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Logitech

Logitech M705 Marathon Wireless Mouse, 2.4 GHz USB Unifying Receiver, 1000 DPI, 5-Programmable Buttons, 3-Year Battery, Compatible with PC, Mac, Laptop, Chromebook - Black

7.8

score

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#10

AUTLEY

AUTLEY Ergonomic Mouse Wireless, 2.4G Rechargeable Vertical Mouse for Medium Large Hands, Carpal Tunnel Mouse with Low Power Warning, Pinky Rest, 800 to 4000 DPI for Laptop, PC, Computer, Matte Black

7.5

score

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PWNAGE Stormbreaker Wireless Magnesium Gaming Mouse 8kHz - 50grams Ultralight Esports Pro Gamer Flawless Professional PAW3395 Optical Sensor 26,000 DPI - 8000Hz -100% PTFE Skates Ergo -Platinum

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PWNAGE Stormbreaker Wireless Magnesium Gaming Mouse 4kHz - 49grams Ultralight Esports Pro Gamer Flawless Professional PAW3395 Optical Sensor 26,000 DPI - 4000Hz -100% PTFE Skates Wireless Ergo -Black

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10 Best Computer Mouse For Large Hands 2025 in the United States

Logitech G305 LIGHTSPEED Wireless Gaming Mouse, Hero 12K Sensor, 12,000 DPI, Lightweight, 6 Programmable Buttons, 250h Battery Life, On-Board Memory, PC/Mac - Black

Amazon Basics Ergonomic 2.4 GHz Wireless Optical Mouse, DPI adjustable, Compatible with PC, Mac, Laptop - Black

Logitech G305 LIGHTSPEED Wireless Gaming Mouse, Hero 12K Sensor, 12,000 DPI, Lightweight, 6 Programmable Buttons, 250h Battery Life, On-Board Memory, PC/Mac - Black

Redragon M602 RGB Wired Gaming Mouse RGB Spectrum Backlit Ergonomic Mouse Griffin Programmable with 8 Backlight Modes, Up to 7200 DPI for Windows PC Gamers (Black)

E-YOOSO Large Wireless Mouse, X-31 Large Mouse for Big Hands, 5-Level 4800 DPI, 6 Button Big Ergo Computer Mouse, 18 Months Battery Life Cordless Mouse for Laptop, Mac, Chromebook, PC, Windows(Black)

Logitech MX Master 3S - Wireless Performance Mouse, Ergo, 8K DPI, Track on Glass, Quiet Clicks, USB-C, Bluetooth, Windows, Linux, Chrome - Graphite - With Free Adobe Creative Cloud Subscription

Logitech MX Vertical Wireless Mouse – Ergonomic Design Reduces Muscle Strain, Move Content Between 3 Windows and Apple Computers, Rechargeable, Graphite

FFJ Wireless Gaming Mouse, 16000 DPI, Tri-Mode 2.4G/USB-C/Dual Bluetooth 5.3 Gaming Mouse Wireless, 9 Backlight, 75Hrs Battery Life, Rechargeable Gaming Mice for PC, Mac, Laptop, PS5, Xbox (Black)

Logitech G309 Lightspeed Wireless Gaming Mouse, Lightweight, LIGHTFORCE Hybrid Switches, Hero 25K Sensor, 86g & 300+ hr Battery Life with AA Battery, 6 Programmable Buttons, PC & Mac - Black

Logitech G PRO X Superlight 2 DEX Lightspeed Wireless Gaming Mouse, 60g Pro-Grade Lightweight Mouse with 5 Programmable Buttons, 44k DPI Sensor, USB-C Charging, for PC/Mac - Black

Logitech G PRO 2 Lightspeed Wireless Gaming Mouse, Right- or Left-Handed Mouse with up to 4 Customizable and Switchable Magnetic Side Buttons, 32k DPI Sensor, USB-C Charging, for PC/Mac - Magenta

PWNAGE Limited Edition Stormbreaker Wireless Magnesium Gaming Mouse 4k- Esports Pro Gamer Flawless Professional PAW3395 Optical Sensor 26,000 DPI- 4000Hz 100% PTFE Skates Ergonomic

Logitech Lift Vertical Ergonomic Mouse, Wireless, Bluetooth or Logi Bolt USB receiver, Quiet clicks, 4 buttons, compatible with Windows/macOS/iPadOS, Laptop, PC - Graphite

Logitech ERGO M575 Wireless Trackball Mouse - Easy thumb control, precision and smooth tracking, ergonomic comfort design, for Windows, PC and Mac with Bluetooth and USB capabilities - Graphite

Logitech Signature M650 L Full Size Wireless Mouse - For Large Sized Hands, 2-Year Battery, Silent Clicks, Customizable Side Buttons, Bluetooth, for PC/Mac/Multi-Device/Chromebook - Black

Logitech M705 Marathon Wireless Mouse, 2.4 GHz USB Unifying Receiver, 1000 DPI, 5-Programmable Buttons, 3-Year Battery, Compatible with PC, Mac, Laptop, Chromebook - Black

AUTLEY Ergonomic Mouse Wireless, 2.4G Rechargeable Vertical Mouse for Medium Large Hands, Carpal Tunnel Mouse with Low Power Warning, Pinky Rest, 800 to 4000 DPI for Laptop, PC, Computer, Matte Black

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PWNAGE SmoothGlide PTFE Rounded Replacement Mouse Skates Feet for G Pro X Superlight GPX, Ultra-Smooth and Durable, 3M Adhesive, Gaming Mouse White

SmoothGlide PTFE Rounded Replacement Mouse Skates Feet for G Pro X 2 Logitech Superlight GPX 2, Ultra-Smooth and Durable, 3M Adhesive, Gaming Mouse White

PWNAGE Stormbreaker Wireless Magnesium Gaming Mouse 8kHz - 50grams Ultralight Esports Pro Gamer Flawless Professional PAW3395 Optical Sensor 26,000 DPI - 8000Hz -100% PTFE Skates Ergo -Platinum

PWNAGE SmoothGlide Universal Dot PTFE Rounded Replacement Mouse Skates Feet for All Mice, Ultra-Smooth and Durable, 3M Adhesive, Gaming Mouse 40 Pieces Round Dots White DIY

PWNAGE Stormbreaker Wireless Magnesium Gaming Mouse 4kHz - 49grams Ultralight Esports Pro Gamer Flawless Professional PAW3395 Optical Sensor 26,000 DPI - 4000Hz -100% PTFE Skates Wireless Ergo -Black