10 Best Cough Suppressants 2025 in the United States

Amazon Basic Care Maximum Strength Mucus DM tablets are designed for those suffering from coughs and chest congestion, making them a solid choice for anyone looking for relief from a cold. The combination of dextromethorphan HBr, a cough suppressant, and guaifenesin, an expectorant, effectively addresses both dry and productive coughs. With a maximum strength formula, these tablets can provide extended relief for up to 12 hours, which is beneficial for those who need uninterrupted rest at night.

The active ingredients work together to ease the intensity of coughing while also helping to clear mucus, making coughs more productive. This dual action can be particularly useful for individuals dealing with both a cough and chest congestion, providing a more comprehensive approach to cold symptoms.

In terms of convenience, the extended-release formulation means that individuals don’t have to take the medication as frequently, which can be a plus. But, depending on personal needs, some might prefer other forms of medication, such as liquids or lozenges, which could provide quicker relief.

Robitussin Adult Maximum Strength Cough Plus Chest Congestion DM Max is a well-rounded option for adults and children over 12 looking for effective relief from cough and chest congestion. Its key strength lies in its dual-action formula, which not only suppresses coughs but also acts as an expectorant, helping to thin and loosen mucus for those who might be dealing with a productive cough. The raspberry flavor adds a pleasant taste, making it easier to take compared to other medicinal options.

One significant advantage is that this product is designed to provide maximum-strength relief while being non-drowsy, making it suitable for daytime use. This is particularly beneficial for those who need to carry on with their daily activities without feeling sleepy or sluggish. The two 8 fl oz bottles offer good value, especially for those who may need to use it over a few days.

Robitussin Adult Maximum Strength Cough Plus Chest Congestion DM Max is a solid choice for adults seeking fast relief from cough and chest congestion.

The Delsym 12 Hour Cough and Nighttime Fast Relief combo pack offers two different cough medicines designed to tackle coughs throughout the day and night. The 12 Hour Cough Liquid contains Dextromethorphan Polistirex, which is an effective cough suppressant that works for up to 12 hours. This means fewer doses and longer relief during the day. It is alcohol-free and comes in a pleasant orange flavor, which may be easier to take for many people.

The Nighttime Fast Relief liquid combines three active ingredients: Dextromethorphan HBr to suppress coughing, Acetaminophen to reduce fever and pain, and Triprolidine, an antihistamine that helps with runny nose and sneezing. This combination aims to help you sleep better by addressing several nighttime symptoms at once. Because it contains multiple ingredients, you should be cautious if you are sensitive to any of them or are taking other medications with acetaminophen or antihistamines. Some users might experience typical side effects like drowsiness from the nighttime formula.

Delsym is the #1 pharmacist-recommended OTC cough suppressant brand, which suggests reliability and trust. If you only need simple cough relief without additional symptom treatment, the nighttime formula might be more than necessary. This combo pack is suited for those looking for all-day cough control plus multi-symptom relief at night, making it a convenient option for managing persistent coughs that interfere with daily activities and sleep.