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10 Best Decongestant For Sinuses 2025 in the United States

From leading brands and best sellers available on the web.

Sponsored

Frida Baby

Frida Baby

Frida Baby NoseFrida Saline Mist Spray, Baby Saline Nasal Spray, Nasal Spray Decongestant to Soften Nasal Passages, Baby Saline Spray for Congestion Relief, 3.4 fl.oz.

#1

Winner

Vicks Pers

Vicks

Vicks Personal Sinus Steam Inhaler, Fast, Targeted Relief for Allergies, Sinus, Cough and Congestion. Use with Vicks VapoPads for Extra Soothing Comfort

Sponsored

Frida Baby

Frida Baby

Frida Baby NoseFrida Saline Mist Spray, Baby Saline Nasal Spray, Nasal Spray Decongestant to Soften Nasal Passages, Baby Saline Spray for Congestion Relief, 3.4 fl.oz.

#2
Vicks Sine

Vicks

Vicks Sinex SEVERE Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Stuffy Nose due to Cold or Allergy, & Nasal Congestion, Sinus Pressure Relief, 265 Sprays x 2

#3
Sudafed PE

Sudafed

Sudafed PE Sinus Congestion Maximum Strength Non-Drowsy Decongestant Tablets, 36 ct

#4
Tylenol Si

TENA

Tylenol Sinus + Headache Daytime Non-Drowsy Relief Caplets, Acetaminophen 325mg, Nasal Decongestant for Sinus Pressure, Headache & Nasal Congestion Relief, 24 ct

#5
Afrin No D

Afrin

Afrin No Drip Severe Congestion Maximum Strength Nasal Spray - 12 Hour Nasal Spray Relief for Nose Congestion, Nasal Swelling, and Allergies - 2 x 0.5 Fl Oz Bottles - Pack of 1

#6
Mucinex Si

Mucinex

Mucinex Sinus Max Severe Congestion & Pain Relief, Maximum Strength Nasal & Sinus Relief, Decongestant for Adults, Acetaminophen Pain Reliever, Guaifenesin Expectorant and Mucus Removal, 20 Caplets

#7
Mucinex Fa

Mucinex

Mucinex Fast-Max Severe Congestion & Cough Medicine, Maximum Strength Symptom Relief, Over-The-Counter Medication, Cold Medicine, Cough Suppressant, Expectorant, Nasal Decongestant, FSA/HSA, 6 FL OZ

#8
GenCare -

GenCare

GenCare - Nasal Decongestant (10mg Tablets) Phenylephrine HCl (300 Tablets Per Bottle) | Value Pack Non Drowsy Sinus and Nasal Congestion Relief | Lower Sinus Pressure Due to Allergies or Illness

#9
Afrin No D

Afrin

Afrin No Drip Extra Moisturizing 12 Hour Nasal Congestion Relief Pump Mist, Sinus Spray Decongestant - 15 mL

#10
Maximum St

Mucinex

Maximum Strength Mucinex Fast-Max Day Cold & Flu & Nightshift Night Severe Cold & Flu All In One, Fast Release, Powerful Multi-Symptom Relief, 40 caplets (24 Day time + 16 Night time)

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