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10 Best Drugstore Hand Cream 2025 in the United States

From leading brands and best sellers available on the web.

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Ora's Amaz

Ora's Amazing Herbal

Ora's Amazing Herbal Ultra Healing Body Butter, Skin Repair Cream for Eczema and Dry Skin, Fragrance Free Body Butter, Unscented Moisturizer, Organic Shea Butter, 2 oz, Made in the USA

#1

Winner

L'Occitane

L'Occitane

L'Occitane Fast-Absorbing 20% Shea Butter Hand Cream, 1 Ounce

Sponsored

Ora's Amaz

Ora's Amazing Herbal

Ora's Amazing Herbal Ultra Healing Body Butter, Skin Repair Cream for Eczema and Dry Skin, Fragrance Free Body Butter, Unscented Moisturizer, Organic Shea Butter, 2 oz, Made in the USA

#2
O'Keeffe's

O'Keeffe's

O'Keeffe's Working Hands Hand Cream for Extremely Dry; Cracked Hands; 3.4 Ounce Jar; (Pack 1)

#3
O'Keeffe's

O'Keeffe's

O'Keeffe's Working Hands Hand Cream; Relieves and Repairs Extremely Dry Hands; 3 oz Tube; (Pack of 2)

#4
eos Shea B

eos

eos Shea Better Hand Cream - Coconut, Natural Shea Butter Hand Lotion and Skin Care, 24 Hour Hydration with Shea Butter & Oil, 2.5 oz, Packaging May Vary

#5
Moroccanoi

Moroccanoil

Moroccanoil Hand Cream Ambiance de Plage, 1.4 Fl Oz

#6
Gold Bond

Gold Bond

Gold Bond Healing Hand Cream, 3 oz., With Aloe, Moisture That Lasts Through Handwashing

#7
La Roche-P

La Roche-Posay

La Roche-Posay Cicaplast Hand Cream, Instant Relief Moisturizing Dry Hands Shea Butter Lotion for Dry Cracked Hands, Non Greasy, Fragrance Free, 1.69 Fl Oz (Pack of 1)

#8
O'Keeffe's

O'Keeffe's

O'Keeffe's Working Hands Hand Cream, For Extremely Dry, Cracked Hands, 6.8 oz Jar (Value Size, Pack of 1)

#9
Retinol An

Retinol

Retinol Anti-Aging Hand Cream – The Original Retinol Brand For Younger Looking Hands –Rich, Velvety Conditions & Protects Skin, Nails & Cuticles – Vitamin A Minimizes Age’s Effect on Skin

#10
Nécessaire

Nécessaire

Nécessaire - The Hand Cream for Women & Men with 5 Ceramides & Peptides, Fragrance-Free Hand Lotion, Fast-Absorbing, Non-Greasy. - 2.2 fl oz.

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Yes To Watermelon Daily Hand Cream, Hydrating & Creamy Texture To Provide Instant Moisturization Without Greasy Residue, With Shea Butter & Antioxidants, Natural, Vegan & Cruelty Free, 3 Oz

Yes To Watermelon Daily Hand Cream, Hydrating & Creamy Texture To Provide Instant Moisturization Without Greasy Residue, With Shea Butter & Antioxidants, Natural, Vegan & Cruelty Free, 3 Oz

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Yon-Ka Sweet Orange Shea Butter Hand Cream (50ml) Intensely Norishing for Dry Hands, Vitamins E and Grape Seed Oil Soften and Repair, Fragrant Manarin and Citrus Scent, Nourish Nails and Cuticles

Yon-Ka Sweet Orange Shea Butter Hand Cream (50ml) Intensely Norishing for Dry Hands, Vitamins E and Grape Seed Oil Soften and Repair, Fragrant Manarin and Citrus Scent, Nourish Nails and Cuticles

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Ultra Healing Body Butter, Intensive Moisturizer For Dry Skin, Spearmint & Bergamot Essential Oil, Ora’s Amazing Herbal, 1 oz, Peppermint Field Scent

Ultra Healing Body Butter, Intensive Moisturizer For Dry Skin, Spearmint & Bergamot Essential Oil, Ora’s Amazing Herbal, 1 oz, Peppermint Field Scent

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Ultra Healing Body Butter, Intensive Moisturizer For Dry Skin, Spearmint & Bergamot Essential Oil, Ora’s Amazing Herbal, 8 oz, Peppermint Field Scent

Ultra Healing Body Butter, Intensive Moisturizer For Dry Skin, Spearmint & Bergamot Essential Oil, Ora’s Amazing Herbal, 8 oz, Peppermint Field Scent

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Ultra Healing Body Butter, Intensive Moisturizer For Dry Skin, Spearmint & Bergamot Essential Oil, Ora’s Amazing Herbal, 2 oz, Peppermint Field Scent

Ultra Healing Body Butter, Intensive Moisturizer For Dry Skin, Spearmint & Bergamot Essential Oil, Ora’s Amazing Herbal, 2 oz, Peppermint Field Scent

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