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Heartburn Medicines Over The Counter

10 Best Heartburn Medicines Over The Counter 2025 in the United States

Name: Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg, Treats Frequent Heartburn, Acid Reducer, Heartburn Medicine, 42 Count (Pack of 1)
Brand: Amazon Basic Care
Price: 13.49 USD
Availability: InStock

From leading brands and best sellers available on the web.

Dr. Barry's Reflux Essentials - Natural Support for Digestive and Stomach Health, Dietary Supplement for Heartburn and Indigestion, 60 Capsules - 30 Day Supply (1)

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Winner

Amazon Basic Care

Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg, Treats Frequent Heartburn, Acid Reducer, Heartburn Medicine, 42 Count (Pack of 1)

9.9

score

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Dr. Barry's Reflux Essentials - Natural Support for Digestive and Stomach Health, Dietary Supplement for Heartburn and Indigestion, 60 Capsules - 30 Day Supply (1)

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HealthCareAisle

HealthCareAisle Omeprazole 20 mg, 42 Delayed-Release Capsules - Acid Reducer, Treats Frequent Heartburn, 42 Count (Pack of 1)

9.8

score

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Pepcid

Pepcid AC Maximum Strength Heartburn Relief Tablets, Prevents & Relieves Heartburn Due to Acid Indigestion & Sour Stomach, 20mg of Famotidine to Reduce & Control Acid, Fast-Acting, 50 Ct

9.6

score

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Nexium

Nexium 24HR ClearMinis Acid Reducer Heartburn Relief Delayed Release Capsules For All-Day And All-Night Protection From Frequent Heartburn, Heartburn Medicine With Esomeprazole Magnesium - 42 Count

9.4

score

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Amazon Basic Care

Amazon Basic Care Esomeprazole Magnesium Delayed Release Capsules, 20 mg, Acid Reducer, Heartburn Medicine, 42 Count

9.1

score

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GoodSense

GoodSense Omeprazole Delayed Release Tablets 20 mg, Stomach Acid Reducer for Frequent Heartburn Treatment, 14 Count (Pack of 3)

8.9

score

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Tagamet

Tagamet Acid Reducer, Cimetidine 200mg, 30 Tablets, 3 Pack

8.6

score

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Amazon Basic Care

Amazon Basic Care Lansoprazole Delayed Release Capsules, 15 mg, Proton Pump Inhibitor, Treats Frequent Heartburn, 24 Hour Heartburn Medicine, 42 Count

8.3

score

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Pepcid

Pepcid AC Original Strength Heartburn Relief Tablets, Prevents & Relieves Heartburn Due to Acid Indigestion & Sour Stomach, 10 mg Famotidine to Reduce & Control Acid, Fast-Acting, 90 Ct

8.1

score

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#10

Zantac

Zantac 360 Maximum Strength Tablets, 100 Count, Heartburn Prevention and Relief, 20 mg

7.8

score

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More products we considered

Organic Sodium Bicarbonate Alkaline Supplement For Alkalinity. Support Kidneys & Stomach Acid Neutralizer with Alkaline Superfoods. Sodium Bicarbonate Powder Kidney Immune Support Antacid Sports 2 LB.

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CALMING BLENDS Acid Reflux Loose Leaf Tea | Acid Reflux, Heartburn & Indigestion | Caffeine-Free | 36 Cups

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Organic Sodium Bicarbonate Alkaline 650 mg Capsules - Enhanced Kidney Support, Stomach Acid Neutralizer with Alkalizing Superfoods, Immune & Sports Performance Aid, Fast-Acting Antacid – 120 Caps

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Nature’s Sodium Bicarbonate Organic Use Aluminum Free Baking Soda. No Chemical Pure Baking Soda Powder For Health & Wellness. Sodium Bicarbonate 1lb

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How do we rank products for you?

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10 Best Heartburn Medicines Over The Counter 2025 in the United States

Dr. Barry's Reflux Essentials - Natural Support for Digestive and Stomach Health, Dietary Supplement for Heartburn and Indigestion, 60 Capsules - 30 Day Supply (1)

Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg, Treats Frequent Heartburn, Acid Reducer, Heartburn Medicine, 42 Count (Pack of 1)

Dr. Barry's Reflux Essentials - Natural Support for Digestive and Stomach Health, Dietary Supplement for Heartburn and Indigestion, 60 Capsules - 30 Day Supply (1)

HealthCareAisle Omeprazole 20 mg, 42 Delayed-Release Capsules - Acid Reducer, Treats Frequent Heartburn, 42 Count (Pack of 1)

Pepcid AC Maximum Strength Heartburn Relief Tablets, Prevents & Relieves Heartburn Due to Acid Indigestion & Sour Stomach, 20mg of Famotidine to Reduce & Control Acid, Fast-Acting, 50 Ct

Nexium 24HR ClearMinis Acid Reducer Heartburn Relief Delayed Release Capsules For All-Day And All-Night Protection From Frequent Heartburn, Heartburn Medicine With Esomeprazole Magnesium - 42 Count

Amazon Basic Care Esomeprazole Magnesium Delayed Release Capsules, 20 mg, Acid Reducer, Heartburn Medicine, 42 Count

GoodSense Omeprazole Delayed Release Tablets 20 mg, Stomach Acid Reducer for Frequent Heartburn Treatment, 14 Count (Pack of 3)

Tagamet Acid Reducer, Cimetidine 200mg, 30 Tablets, 3 Pack

Amazon Basic Care Lansoprazole Delayed Release Capsules, 15 mg, Proton Pump Inhibitor, Treats Frequent Heartburn, 24 Hour Heartburn Medicine, 42 Count

Pepcid AC Original Strength Heartburn Relief Tablets, Prevents & Relieves Heartburn Due to Acid Indigestion & Sour Stomach, 10 mg Famotidine to Reduce & Control Acid, Fast-Acting, 90 Ct

Zantac 360 Maximum Strength Tablets, 100 Count, Heartburn Prevention and Relief, 20 mg

Organic Sodium Bicarbonate Alkaline Supplement For Alkalinity. Support Kidneys & Stomach Acid Neutralizer with Alkaline Superfoods. Sodium Bicarbonate Powder Kidney Immune Support Antacid Sports 2 LB.

CALMING BLENDS Acid Reflux Loose Leaf Tea | Acid Reflux, Heartburn & Indigestion | Caffeine-Free | 36 Cups

Organic Sodium Bicarbonate Alkaline 650 mg Capsules - Enhanced Kidney Support, Stomach Acid Neutralizer with Alkalizing Superfoods, Immune & Sports Performance Aid, Fast-Acting Antacid – 120 Caps

Nature’s Sodium Bicarbonate Organic Use Aluminum Free Baking Soda. No Chemical Pure Baking Soda Powder For Health & Wellness. Sodium Bicarbonate 1lb

FAQ

What is the best over-the-counter medicine for heartburn?

How long can I safely take over-the-counter heartburn medicines?

Are there any side effects of taking over-the-counter heartburn medicines?

Can over-the-counter heartburn medicines be taken during pregnancy?

Do over-the-counter heartburn medicines interact with other medications?

10 Best Heartburn Medicines Over The Counter 2025 in the United States

Dr. Barry's Reflux Essentials - Natural Support for Digestive and Stomach Health, Dietary Supplement for Heartburn and Indigestion, 60 Capsules - 30 Day Supply (1)

Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg, Treats Frequent Heartburn, Acid Reducer, Heartburn Medicine, 42 Count (Pack of 1)

Dr. Barry's Reflux Essentials - Natural Support for Digestive and Stomach Health, Dietary Supplement for Heartburn and Indigestion, 60 Capsules - 30 Day Supply (1)

HealthCareAisle Omeprazole 20 mg, 42 Delayed-Release Capsules - Acid Reducer, Treats Frequent Heartburn, 42 Count (Pack of 1)

Pepcid AC Maximum Strength Heartburn Relief Tablets, Prevents & Relieves Heartburn Due to Acid Indigestion & Sour Stomach, 20mg of Famotidine to Reduce & Control Acid, Fast-Acting, 50 Ct

Nexium 24HR ClearMinis Acid Reducer Heartburn Relief Delayed Release Capsules For All-Day And All-Night Protection From Frequent Heartburn, Heartburn Medicine With Esomeprazole Magnesium - 42 Count

Amazon Basic Care Esomeprazole Magnesium Delayed Release Capsules, 20 mg, Acid Reducer, Heartburn Medicine, 42 Count

Organic Sodium Bicarbonate Alkaline Capsules - Boosts Kidney Health, Neutralizes Stomach Acid with Alkalizing Superfoods, Supports Immune System & Athletic Performance, Rapid Relief Antacid 2 Pack

Baking Soda Capsules 650mg Pure Baking Soda Aluminum Free Organic Use. Natural Baking Soda 120 Caps

Bicarbonato de Sodio clásico 650 mg USO orgánico Natural Pastillas de bicarbonato de Sodio en polvo Tabletas de bicarbonato de Sodio (cápsulas) Alcalinidad del ácido del estómago 120 cápsulas

Classic Sodium Bicarbonate 650mg Natural Organic Use Sodium Bicarbonate Powder Pills Sodium Bicarbonate Tablets (caps) Stomach Acid Alkalinity 120caps

Dr. Barry's Reflux Essentials - Natural Support for Digestive and Stomach Health, 60 Capsules - 30 Day Supply (1)

GoodSense Omeprazole Delayed Release Tablets 20 mg, Stomach Acid Reducer for Frequent Heartburn Treatment, 14 Count (Pack of 3)

Tagamet Acid Reducer, Cimetidine 200mg, 30 Tablets, 3 Pack

Amazon Basic Care Lansoprazole Delayed Release Capsules, 15 mg, Proton Pump Inhibitor, Treats Frequent Heartburn, 24 Hour Heartburn Medicine, 42 Count

Pepcid AC Original Strength Heartburn Relief Tablets, Prevents & Relieves Heartburn Due to Acid Indigestion & Sour Stomach, 10 mg Famotidine to Reduce & Control Acid, Fast-Acting, 90 Ct

Zantac 360 Maximum Strength Tablets, 100 Count, Heartburn Prevention and Relief, 20 mg

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Organic Sodium Bicarbonate Alkaline Supplement For Alkalinity. Support Kidneys & Stomach Acid Neutralizer with Alkaline Superfoods. Sodium Bicarbonate Powder Kidney Immune Support Antacid Sports 2 LB.

CALMING BLENDS Acid Reflux Loose Leaf Tea | Acid Reflux, Heartburn & Indigestion | Caffeine-Free | 36 Cups

Organic Sodium Bicarbonate Alkaline 650 mg Capsules - Enhanced Kidney Support, Stomach Acid Neutralizer with Alkalizing Superfoods, Immune & Sports Performance Aid, Fast-Acting Antacid – 120 Caps

Nature’s Sodium Bicarbonate Organic Use Aluminum Free Baking Soda. No Chemical Pure Baking Soda Powder For Health & Wellness. Sodium Bicarbonate 1lb

FAQ

What is the best over-the-counter medicine for heartburn?

How long can I safely take over-the-counter heartburn medicines?

Are there any side effects of taking over-the-counter heartburn medicines?

Can over-the-counter heartburn medicines be taken during pregnancy?

Do over-the-counter heartburn medicines interact with other medications?