10 Best Hyaluronic Acid Serums 2025 in the United States

The La Roche-Posay Hyalu B5 Pure Hyaluronic Acid Serum is a strong contender in the hyaluronic acid serum market, especially for those looking to tackle fine lines, wrinkles, and dehydrated skin. This serum features a concentrated blend of pure hyaluronic acid, which is known for its hydrating and plumping properties. The inclusion of Vitamin B5 and madecassoside adds to its skin-repairing benefits, making it particularly effective for dry and sensitive skin types.

Users have reported noticeable improvements in skin hydration, softness, and suppleness within just four weeks of use, which is impressive. The product is also oil-free, noncomedogenic, and allergy-tested, ensuring it is safe for all skin types, including sensitive ones. However, the serum does have a scent, which may not be suitable for everyone, particularly those with fragrance sensitivities.

The packaging is practical and the serum is easy to apply, but the small bottle size (1.45 ounces) might mean you’ll need to repurchase it relatively frequently if used daily. La Roche-Posay is a reputable brand with positive reviews, giving consumers confidence in the product’s effectiveness. This serum is ideal for those looking to add a potent anti-aging and hydrating step to their skincare routine.

The Ordinary Hyaluronic Acid 2% + B5 serum is a popular choice for those seeking effective hydration and improved skin health. With a 2% concentration of hyaluronic acid, it provides significant moisture to the skin. The inclusion of ceramides helps lock in this moisture, supporting the skin’s barrier functions. Additionally, pro-vitamin B5 enhances moisture retention, contributing to smoother, plumper skin and reducing the appearance of fine lines and wrinkles.

This serum uses five types of hyaluronic acid to deliver hydration to various skin layers, ensuring comprehensive moisture retention and skin suppleness. It is suitable for all skin types and is fragrance-free, making it a great option for those with sensitive skin. The serum comes in a 1 fl oz bottle and is packaged to minimize waste, although some users might find the dropper design inconvenient.

The Ordinary is well-regarded for creating affordable, effective skincare solutions, backed by a solid brand reputation. However, the product’s simplicity might not cater to those looking for a more luxurious or multi-functional serum. This serum is highly effective for hydration and improving skin texture, making it ideal for anyone seeking a straightforward and potent hydration solution.

CeraVe Vitamin C Serum with Hyaluronic Acid is designed to provide both brightening and hydrating benefits, making it a solid choice for anyone looking to improve their skin's overall appearance. One of the standout features is its 10% concentration of pure vitamin C, which is known for its antioxidant properties that help brighten the skin and even out the skin tone. The inclusion of hyaluronic acid in the formulation enhances hydration, making it particularly beneficial for those with dry or dehydrated skin.

This serum also boasts a lightweight, gel-like texture that absorbs quickly without leaving a greasy residue, which is ideal for layering with other skincare products. Additionally, it contains three essential ceramides that help support the skin barrier, an important aspect for maintaining skin health, especially as we age.

This serum is fragrance-free and non-comedogenic, making it suitable for various skin types, including sensitive skin. However, some people with very oily or acne-prone skin might want to patch-test it first, as individual reactions can vary. CeraVe's Vitamin C Serum is a versatile option for individuals looking to brighten and hydrate their skin, but potential users should consider their specific skin needs.