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10 Best Motion Sickness Medicines 2025 in the United States

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Our Top Picks

#1

Winner

Bonine Non-Drowsy Motion Sickness Relief - 32 Chewable Tablets with Meclizine HCL 25mg - Non Drowsy Medicine for Nausea or Motion Sickness - Cruise Essentials - Raspberry Flavor

Rating
9.8
Chosen by1,170
Form of Medicine
Onset of Action
Side Effects

Most important from
4118 reviews

Form of Medicine
The product works quickly, within 10 minutes, and fits conveniently in a purse for on-the-go relief.
Onset of Action
The product works quickly, within 10 minutes, and fits conveniently in a purse for on-the-go relief.
Side Effects
Bonine works great for seasickness, even on cruises. No side effects and no drowsiness.

Bonine Non-Drowsy Motion Sickness Relief is a convenient option for those who suffer from nausea or motion sickness. With its active ingredient, Meclizine Hydrochloride 25mg, it promises effective relief without causing drowsiness. This makes it suitable for individuals who need to stay alert, such as drivers or travelers. The chewable tablets are raspberry-flavored and don't require water, which is handy for on-the-go use.

One of the significant strengths of Bonine is its long-lasting effect, providing relief for up to 24 hours. This feature is beneficial for long trips or a full day of activities. Additionally, the product is suitable for adults and children aged 12 and above, making it versatile for family use.

However, there are some drawbacks to consider. Some users may experience side effects such as dry mouth, drowsiness in rare cases, or blurred vision. People with certain health conditions or those taking other medications should consult a healthcare professional before use. Additionally, the onset of action may vary, so it's recommended to take the tablet one hour before travel or anticipated motion sickness. In conclusion, Bonine offers a practical and long-lasting solution for motion sickness without the drowsiness, although users should be aware of potential side effects and consult with a doctor if unsure about suitability.

Rating
9.8
Chosen by1,170
Form of Medicine
Onset of Action
Side Effects

Most important from
4118 reviews

Form of Medicine
The product works quickly, within 10 minutes, and fits conveniently in a purse for on-the-go relief.
Onset of Action
The product works quickly, within 10 minutes, and fits conveniently in a purse for on-the-go relief.
Side Effects
Bonine works great for seasickness, even on cruises. No side effects and no drowsiness.
#2

Bonine MAX Chewable for Motion Sickness Relief - with Meclizine HCL 50mg - Max Strength Formula to Treat Nausea or Motion Sickness - Cruise Essentials - Peppermint - 16 Chewable Tablets

Rating
9.6
Duration of Effect

Most important from
987 reviews

Duration of Effect
Keeps motion sickness in check during long cruises, allowing for a smooth and enjoyable trip.

The Bonine MAX Chewable for Motion Sickness Relief is a strong over-the-counter option designed to combat nausea and motion sickness. Its active ingredient, Meclizine HCL 50mg, is the highest strength available without a prescription, making it suitable for those in need of serious relief. One of its standout features is its ease of use—these peppermint-flavored chewable tablets do not require water, which adds convenience, especially during travel.

The product is effective for up to 24 hours, which is ideal for long trips or continuous exposure to motion, like cruises or road trips. It's especially beneficial for individuals aged 12 and up who frequently experience motion sickness from various activities, from car rides to video games. However, there are some considerations to keep in mind. While the product claims to be non-drowsy, individual reactions can vary, and some users might still experience drowsiness.

Additionally, as a max strength formula, it may not be suitable for those with certain health conditions or for younger children. The product's side effects and health considerations should be carefully reviewed, especially for those with existing health concerns or who are on other medications. In summary, Bonine MAX is a potent and convenient option for motion sickness relief but should be used with caution and awareness of potential side effects.

Rating
9.6
Duration of Effect

Most important from
987 reviews

Duration of Effect
Keeps motion sickness in check during long cruises, allowing for a smooth and enjoyable trip.
#3

Dramamine Motion Sickness Relief Less Drowsey Formula, 8 Count (Pack of 1)

Rating
9.3
Duration of Effect
Side Effects

Most important from
19545 reviews

Duration of Effect
Works great for long journeys, including a 10-hour flight, with no need for a second dose.
Side Effects
This has been a total game-changer for motion sickness from video games, allowing enjoyment without nausea and without feeling drowsy.

Dramamine Motion Sickness Relief Less Drowsy Formula is designed to alleviate motion sickness symptoms such as nausea, dizziness, and vomiting. It is formulated to cause less drowsiness compared to some other options, making it suitable for activities where staying alert is important.

The product has a long-lasting effect, providing relief for up to 24 hours, which is beneficial for long journeys or trips. Its compact travel vial makes it convenient to carry along wherever you go.

This product is highly recommended by pharmacists and has a strong reputation in the market. However, like any medication, it may have side effects and it's always a good idea to consult a healthcare professional, especially for children or those with specific health conditions.

Rating
9.3
Duration of Effect
Side Effects

Most important from
19545 reviews

Duration of Effect
Works great for long journeys, including a 10-hour flight, with no need for a second dose.
Side Effects
This has been a total game-changer for motion sickness from video games, allowing enjoyment without nausea and without feeling drowsy.

Buying Guide for the Best Motion Sickness Medicines

Choosing the right motion sickness medicine can make a significant difference in your travel experience. Motion sickness occurs when there is a disconnect between what your eyes see and what your inner ear senses, leading to symptoms like nausea, dizziness, and vomiting. The right medicine can help alleviate these symptoms and make your journey more comfortable. Here are some key specifications to consider when selecting a motion sickness medicine.
Active IngredientThe active ingredient is the component in the medicine that helps prevent or treat motion sickness. Common active ingredients include dimenhydrinate, meclizine, and scopolamine. Dimenhydrinate is often used for short trips and provides quick relief, while meclizine is suitable for longer trips and has a longer-lasting effect. Scopolamine is typically used for severe cases and is available in patch form for extended relief. Choose the active ingredient based on the duration and severity of your symptoms.
Form of MedicineMotion sickness medicines come in various forms, including tablets, chewable tablets, liquid, and patches. Tablets and chewable tablets are convenient and easy to carry, making them ideal for short trips. Liquid forms are suitable for children or those who have difficulty swallowing pills. Patches provide long-lasting relief and are ideal for extended trips or severe symptoms. Consider your personal preference and the ease of use when selecting the form of medicine.
Onset of ActionThe onset of action refers to how quickly the medicine starts to work after taking it. Some medicines, like dimenhydrinate, start working within 30 minutes, making them suitable for last-minute use. Others, like scopolamine patches, need to be applied several hours before travel to be effective. If you need immediate relief, choose a medicine with a quick onset of action. For planned trips, a medicine with a longer onset time may be more appropriate.
Duration of EffectThe duration of effect indicates how long the medicine will provide relief from motion sickness symptoms. Short-acting medicines may last for a few hours, while long-acting options can provide relief for up to 24 hours or more. If you are going on a short trip, a short-acting medicine may be sufficient. For longer journeys, consider a long-acting medicine to ensure continuous relief without the need for frequent dosing.
Side EffectsAll medicines can have side effects, and motion sickness medicines are no exception. Common side effects include drowsiness, dry mouth, and blurred vision. Some medicines may cause more drowsiness than others, which can be a concern if you need to stay alert. If you are sensitive to side effects or need to avoid drowsiness, look for medicines with fewer or milder side effects. Always read the label and consult with a healthcare professional if you have any concerns.
Age and Health ConsiderationsCertain motion sickness medicines may not be suitable for young children, elderly individuals, or those with specific health conditions. For example, some medicines are not recommended for children under a certain age or for individuals with glaucoma or urinary retention. Always check the age recommendations and any health warnings on the label. If you have any health conditions or are taking other medications, consult with a healthcare professional to ensure the medicine is safe for you.

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