10 Best Nitric Oxide Supplements 2025 in the United States

You might confuse Nitric Oxide (chemical formula NO) with laughing gas, nitrous oxide (chemical formula N2O), which was used as an anesthetic. But Nitric Oxide is no laughing matter. Your body manufactures it when processing proteins. More specifically, it’s produced by the inner lining of your blood vessels--and Nitric Oxide makes your muscles relax and your blood vessels dilate. When your blood vessels dilate, your blood flows more freely--which allows your muscles to be able to work harder, without feeling fatigued. It can also increase your cardiovascular health. Also, drugs that seek to improve sexual health utilize the body’s Nitric Oxide pathway--and, by increasing blood flow, Nitric Oxide supplements can play a role here as well.

But you’ll see quite a few products on the market, each offering Nitric Oxide in different forms. They’ll also have other vitamins and minerals, to improve your overall health. You’d probably like to do some more research before deciding on a Nitric Oxide supplement that’s right for you. We’ll go through some of the options on the market, to help you decide.

Many companies will produce Nitric Oxide supplements in two forms: powder, and pills.

• Powder: Many companies market a Nitric Oxide supplement in powder form, such as beetroot powder. Beetroots are considered a “superfood”, with Vitamins A, B1, B2, B3, B5, B6, C, and calcium, iron, potassium, and iron. Beets are also rich in nitrates, from which the body produces Nitric Oxide. The advantage of such powders is that you can mix them with water and make a refreshing drink, or mix it into a smoothie. An example is Snap Nitric Oxide Organic Beet Powder.

Snap Nitric Oxide Organic Beet Powder

• Capsules: Some would prefer capsules since you can carry them along with you anywhere and take them when convenient. You’ll see Nitric Oxide capsules as large as 1600 mg, such as those made by Double Dragon Organics.

Double Dragon Organics Nitric Oxide Boost

• Lowering blood pressure: Nitric Oxide is a vasodilator, making the blood vessels expand. This should help reduce blood pressure. And, although studies have not produced conclusive results, people notice an improvement in their blood pressure.

• Help for erectile dysfunction: Also, one of the causes of ED is if the penis doesn’t receive a proper blood flow. (People who suffer atherosclerosis, with plaques forming on the blood vessels, also complain of ED.) Nitric Oxide supplements can therefore be of assistance in this area as well--even though the results can be somewhat subjective.

• Better exercise workouts: Some say that a Nitric Oxide supplement gave them a definite improvement in the amount of weight that they can lift, as well as the number of reps that they can perform. This all can lead to improved muscle gain as well. Also, people who suffer from high blood pressure, or from cystic fibrosis, said that they could go for longer walks without feeling fatigued.

There are certain ingredients that you’ll find in many nitric oxide supplements:

• L-Arginine, is an amino acid that is broken down by the body’s enzymes, producing nitric oxide. Nitric oxide dilates the body’s blood vessels, increasing blood flow and preventing blockage of blood vessels. There are two types of L-Arginine: L-Arginine, and L-Arginine AKG.

• L-Citrulline, another amino acid found naturally in cucumber, squash, pumpkin, and watermelon. It is converted by the body to L-Arginine, so it also increases the amount of nitric oxide in the body.

• Branch chain amino acids (BCAA): These are building blocks of proteins, that you’ll also see in Nitric Oxide supplements. Your muscles will use these amino acids as a source of energy. So, a supplement with BCAA will help you develop more muscle mass, and allow you to work out longer without feeling fatigued.

• Medium-chain Triglycerides (MCTs): These are compounds that allow your cells to get energy more quickly, by being absorbed quickly into the bloodstream and thus by the cells.

• Other vitamins and minerals: If you’re already buying a supplement, there’s nothing wrong with some additional vitamins. Since Nitric Oxide will increase blood flow, your body will get these vitamins more efficiently as well. The Snap Supplements Beet Root Powder also contains Vitamin C, Vitamins B3, B6, and B12.

• Double Dragon Organics Nitric Oxide Booster Supplement comes in capsule form, with L-Arginine, L-Citrulline, and beetroot, to accelerate the body’s production of Nitric Oxide. This increases blood flow, which in turn gives you greater endurance. You can also buy a two-pack, which saves money.

Double Dragon Organics Nitric Oxide Booster Supplement

• Snap Supplements Organic Nitric Oxide Beets Root Powder is formulated to help your body optimize its production of Nitric Oxide. It can help you maintain cardiovascular health, including a healthy blood pressure level. It can also improve your immune system, your brain’s neuroplasticity, and relieve muscle fatigue.

Snap Supplements Organic Nitric Oxide Beets Root Powder

• Irwin Naturals Nitric Oxide Pre-Sport Softgels contains L-Citrulline and Medium Chain Triglycerides, which provide cellular energy. Irwin Naturals’ formula also contains Yerba Maté and Ginseng, which are traditionally used in natural medicine for increasing energy levels, and Ginko, which is for better circulation.

Irwin Naturals Nitric Oxide Pre-Sport Softgels

• Force Factor Score! Nitric Oxide Libido Enhancer contains L-Citrulline for Nitric Oxide production, as well as a number of natural herbs that are traditionally known to increase sexual performance and desire: Ginko Biloba, horny goat weed, Tribulus Terrestris, black maca, ashwagandha, and more.

Force Factor Score! Nitric Oxide Libido Enhancer