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10 Best Otc Allergy Medicines 2025 in the United States

From leading brands and best sellers available on the web.

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Profession

Professional Botanicals

Professional Botanicals Sinus – Natural Herbal Allergy Relief Supplement – 60 Vegetarian Capsule

#1

Winner

Amazon Bas

Amazon Basic Care

Amazon Basic Care All Day Allergy, Cetirizine Hydrochloride Tablets, Antihistamine, 10 mg, 365 Count (Pack of 1)

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Profession

Professional Botanicals

Professional Botanicals Sinus – Natural Herbal Allergy Relief Supplement – 60 Vegetarian Capsule

#2
Claritin 2

Claritin

Claritin 24hr Non-Drowsy Allergy Relief, Loratadine Tablets - 100ct

#3
Zyrtec 24

Zyrtec

Zyrtec 24 Hour Allergy Relief Tablets, Indoor & Outdoor Allergy Medicine with 10 mg Cetirizine HCl Antihistamine for Allergies, Bundle of one, 30 ct Bottle & Three,1 ct Travel Packs

#4
Amazon Bas

Amazon Basic Care

Amazon Basic Care Complete Allergy Relief, Diphenhydramine HCl 25 mg, Relieves Symptoms, Antihistamine Tablets, 400 Count

#5
Astepro Na

Astepro

Astepro Nasal Spray, 24-Hour Allergy Relief, Steroid-Free Antihistamine, Nasal Congestion, Runny & Itchy Nose, For Adults and Children 6 Years and Older, 200 Metered Sprays (1 Bottle)

#6
Benadryl U

Benadryl

Benadryl Ultratabs Antihistamine Allergy Relief Medicine, Diphenhydramine HCl Tablets for Relief of Cold & Allergy Symptoms Such as Sneezing, Runny Nose, & Itchy Eyes & Throat, 100 ct

#7
Zyrtec 24

Zyrtec

Zyrtec 24 Hour Allergy Relief Tablets, Indoor & Outdoor Allergy Medicine with 10 mg Cetirizine HCl per Antihistamine Tablet, Relief of Allergies, 60 ct

#8
Xyzal Alle

Xyzal

Xyzal Allergy Pills, 24-Hour Allergy Relief, 55-Count, Original Prescription Strength

#9
KIRKLAND S

KIRKLAND

KIRKLAND SIGNATURE Aller-Flo Fluticasone Propionate (Glucorticoid) 5 Bottles x 120 Metered Sprays 0.54 Fl OZ per Bottle (15.8 mL x 5) 2.70 OZ Total (79 mL Total) 600 Total Sprays Total, 1-Pack

#10
Zyrtec 24

Zyrtec

Zyrtec 24 Hour Allergy Relief Liquid Gels, Antihistamine Capsules with Cetirizine Hydrochloride Allergy Medicine for All-Day Relief from Runny Nose, Sneezing, Itchy Eyes & More, 40 ct

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