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10 Best Otc Flea Meds For Dogs 2025 in the United States

From leading brands and best sellers available on the web.

Sponsored

Advecta Ul

Advecta

Advecta Ultra Flea and Tick Prevention for Dogs - Dog and Puppy Treatment and Control - Mosquito Repellent - XL, Fast Acting Waterproof Topical Drops, 6 Month Supply

#1

Winner

Frontline

Frontline

Frontline Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 8 Treatments

Sponsored

Advecta Ul

Advecta

Advecta Ultra Flea and Tick Prevention for Dogs - Dog and Puppy Treatment and Control - Mosquito Repellent - XL, Fast Acting Waterproof Topical Drops, 6 Month Supply

#2
Capstar (n

Capstar

Capstar (nitenpyram) for Dogs, Fast-Acting Oral Flea Treatment for Dogs over 25+ lbs, Vet-Recommended Flea Medication Tablets Start Killing Fleas in 30 Minutes, 6 Doses

#3
K9 Advanti

K9 Advantix

K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 6-Mo Supply

#4
FRONTLINE

Frontline

FRONTLINE Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs., 3 Treatments

#5
K9 Advanti

K9 advantix

K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 2-Mo Supply

#6
PetArmor C

PetArmor

PetArmor CAPACTION (nitenpyram) Oral Flea Treatment for Dogs, Fast Acting Tablets Start Killing Fleas in 30 Minutes, Dogs Over 25 lbs, 6 Doses (Pack of 1) (Packaging May Vary)

#7
Activate I

TevraPet

Activate II Flea and Tick Prevention for Dogs | 4 Count | Large Dogs 21-55 lbs | Topical Drops | 4 Months Flea Treatment

#8
Frontline

Frontline

Frontline Plus Flea and Tick Treatment for Medium Dogs Up to 23 to 44 lbs. 3 Treatments

#9
Advecta Ul

Advecta

Editor’s Choice

Advecta Ultra Flea And Tick Prevention For Dogs - Dog and Puppy Treatment and Control - Mosquito Repellent - Small, Fast Acting Waterproof Topical Drops, 4 Month Supply

#10
FRONTLINE

Frontline

FRONTLINE Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs., 3 Treatments

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