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10 Best Otc Sleep Aids 2025 in the United States

From leading brands and best sellers available on the web.

Sponsored

12-in-1 Me

MEDCHOICE

12-in-1 Melatonin Capsules - Melatonin 5mg Natural Sleep Aids for Adults - Magnesium Glycinate 500mg, Ashwagandha, L Theanine, Valerian Root, GABA, 5-HTP, Sleep Supplement for Adults, Pack of 1

#1

Winner

ZzzQuil PU

ZzzQuil

Editor’s Choice

ZzzQuil PURE Zzzs Melatonin Sleep Aid Gummies, Helps You Fall Asleep Naturally, Wildberry Vanilla Flavor, Chamomile Lavender & Valerian Root, 2mg per gummy, 72 Count

Sponsored

12-in-1 Me

MEDCHOICE

12-in-1 Melatonin Capsules - Melatonin 5mg Natural Sleep Aids for Adults - Magnesium Glycinate 500mg, Ashwagandha, L Theanine, Valerian Root, GABA, 5-HTP, Sleep Supplement for Adults, Pack of 1

#2
Unisom Sle

Unisom

Unisom SleepTabs, Nighttime Sleep-aid, Doxylamine Succinate, 80 Tablets

#3
Natrol Mel

Natrol

Natrol Melatonin 10mg, Dietary Supplement for Restful Sleep, 90 Strawberry-Flavored Gummies, 45 Day Supply

#4
Tylenol PM

Tylenol

Tylenol PM Extra Strength Nighttime Pain Reliever & Sleep Aid Caplets, 500 mg Acetaminophen & 25 mg Diphenhydramine HCl, Relief for Nighttime Aches & Pains, Non-Habit Forming, 100 ct

#5
Natrol Sle

Natrol

Natrol Sleep Melatonin 10mg Fast Dissolve Tablets, Nighttime Sleep Aid for Adults, 100 Strawberry-Flavored Melatonin Tablets, 100 Day Supply

#6
ZzzQuil, S

ZzzQuil

ZzzQuil, Sleep Aid, Nighttime Sleep Aid Liquid, 50 mg Diphenhydramine HCl, Fall Asleep Fast, Non-Habit Forming, Warming Berry Flavor, 12 FL OZ x 2 (Twin Pack)

#7
Amazon Bas

Amazon Basic Care

Amazon Basic Care Nighttime Sleep Aid Tablets for Adults, Doxylamine Succinate 25 mg, 96 Count

#8
HealthA2Z

HealthA2Z

HealthA2Z Sleep Aid, Diphenhydramine Softgels, 50mg, Supports Deeper, Restful Sleeping, Non Habit-Forming (250 Counts)

#9
ZzzQuil UL

ZzzQuil

ZzzQuil ULTRA, Sleep Aid, Nighttime Sleep Aid, 25 mg Doxylamine Succinate, From Makers of Nyquil, Non- Habit Forming, Fall Asleep Fast, Stay Asleep Longer, 48 Count

#10
ZzzQuil, N

ZzzQuil

ZzzQuil, Nighttime Sleep Aid LiquiCaps, 25 mg Diphenhydramine HCl, No.1 Sleep-Aid Brand, Non-Habit Forming, Fall Asleep Fast, 72 Count

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