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10 Best Over The Counter Medicine For Colds 2025 in the United States

From leading brands and best sellers available on the web.
#1

Winner

Tylenol Ex

Tylenol

Tylenol Extra Strength Acetaminophen Rapid Release Gels, Pain Reliever & Fever Reducer, 100 ct

#2
Amazon Bas

Amazon Basic Care

Amazon Basic Care Complete Allergy Relief, Diphenhydramine HCl 25 mg, Relieves Symptoms, Antihistamine Tablets, 400 Count

#3
Vicks DayQ

Vicks

Vicks DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, & Cough, 48ct

#4
Mucinex Fa

Mucinex

Mucinex Fast-Max Cold and Flu & Nightshift Severe Cold and Flu Medicine for Adults, Over-the-Counter Medication Combo Pack for Sore Throat Relief, Decongestant, Cough & Cold Medicines, 2 x 6 Fl Oz

#5
Boiron Osc

Boiron

Boiron Oscillococcinum for Relief from Flu-Like Symptoms of Body Aches, Headache, Fever, Chills, and Fatigue - 6 Count

#6
Mucinex Fa

Mucinex

Mucinex FastMax DM Max Cold & Flu Liquid - Thins Mucus, Relieves Cough, Chest Congestion, Pain, Fever, Sneezing, Sore Throat, Runny Nose

#7
Vicks DayQ

Vicks

Vicks DayQuil & NyQuil SEVERE Honey Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, & Cough, Honey Flavor, 2x12 OZ

#8
Abreva 10

Abreva

Abreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Tube x 2

#9
Vicks DayQ

Vicks

Vicks DayQuil Cold & Flu Medicine, Non-Drowsy Powerful Multi-Symptom Daytime Relief for Headache, Fever, Sore Throat, Minor Aches and Pains, Nasal Congestion, Sinus Pressure and Cough, 48 Liquicaps

#10
Vicks NyQu

Vicks

Vicks NyQuil Cold and Flu Relief Liquid Medicine, Powerful Multi-Symptom Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches and Pains, Sneezing, Runny Nose, and Cough, 48 Liquicaps

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