10 Best Pet Stain Removers 2025 in the United States

The Simple Solution Extreme Pet Stain and Odor Remover is an enzymatic cleaner designed to tackle the toughest pet stains and odors with three times the cleaning power of regular formulas. This product is highly effective for removing dog and cat messes like urine, feces, and vomit from various surfaces including carpet, upholstery, bedding, fabrics, and other water-safe areas. Its enzymatic formula not only cleans but also helps prevent pets from marking the same spot again.

Additionally, it is safe to use around children and pets when used as directed, making it a family-friendly option. Ease of use is highlighted, promising a hassle-free cleaning experience. However, the product's large volume of one gallon might be cumbersome for some users to handle and store. While it is effective on many surfaces, it may not be suitable for non-water-safe materials.

Users should ensure they follow the directions carefully to avoid any potential issues. This cleaner is ideal for pet owners looking for a powerful and safe solution to maintain a clean and fresh home environment.

Nature’s Miracle Advanced Stain and Odor Eliminator Dog Spray is designed for tackling severe dog messes including urine, diarrhea, and vomit. The enzymatic formula is a standout feature, as it continues to break down and eliminate stains and odors as long as the bio-based mess is present. This makes it highly effective for persistent or tough stains. Additionally, the formula helps discourage resoiling by removing the odor completely, which is beneficial for pet owners dealing with recurring accidents.

The product also leaves a light, fresh scent, which helps to control dog odors and make your home smell clean again. One of the significant advantages of this product is its safety for pets and humans, as it is crafted by a trusted brand known for effective pet stain and odor removal solutions. The liquid sprayer form makes it easy to use, allowing for convenient application on various surfaces.

Despite being labeled as unscented, there is a light fresh scent which might not be preferred by those who are sensitive to fragrances. Additionally, while the enzymatic formula is effective, it requires time to fully break down the stains and odors, which might not offer immediate results for users in need of a quick fix. This product is best suited for pet owners who need a reliable and safe solution to deal with severe pet messes and want to ensure their home remains odor-free.

The Resolve Ultra Pet Odor and Stain Remover Spray is designed to tackle tough pet stains like urine and poop on carpets, upholstery, and area rugs. Its gel formula penetrates deeply to lift stains, which can be helpful for stubborn messes you want removed quickly. It uses Oxi+Odor Stop technology to neutralize odors, leaving your home smelling fresher—an important feature if you have pets frequently causing accidents.

The product is safe to use around pets when directions are followed, which is reassuring for households with animals and children. Although it doesn’t explicitly mention an enzymatic formula, its stain and odor removal methods seem effective for various surfaces commonly affected by pet messes. The spray is easy to apply and from a trusted brand known for cleaning products, adding confidence in its performance.

Since it comes as a gel, some users might find it a bit different from typical liquid sprays, and it’s primarily aimed at carpets and similar fabrics rather than hard surfaces. If you need a reliable cleaner for pet stains on soft surfaces with good odor control and pet-safe qualities, this product fits those needs well.