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10 Best Rated Flea Treatment 2025 in the United States

From leading brands and best sellers available on the web.

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NEXTSTAR F

NEXTSTAR

27%OFF

NEXTSTAR Flea and Tick Prevention for Dogs, Repellent, and Control, Fast Acting Waterproof Topical Drops for Large Dogs, 6 Monthly Doses

#1

Winner

Frontline

Frontline

Frontline Plus Flea and Tick Treatment for Cats Over 1.5 lbs. 3 Treatments

Sponsored

NEXTSTAR F

NEXTSTAR

27%OFF

NEXTSTAR Flea and Tick Prevention for Dogs, Repellent, and Control, Fast Acting Waterproof Topical Drops for Large Dogs, 6 Monthly Doses

#2
Frontline

Frontline

Frontline Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments

#3
Frontline

Frontline

Frontline Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs. 3 Treatments

#4
PetArmor P

PetArmor

PetArmor Plus Flea and Tick Prevention for Dogs, Dog Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting, Large Dogs (45-88 lbs)

#5
Capstar (n

Capstar

Capstar (nitenpyram) for Dogs, Fast-Acting Oral Flea Treatment for Dogs over 25+ lbs, Vet-Recommended Flea Medication Tablets Start Killing Fleas in 30 Minutes, 6 Doses

#6
Capstar (n

Capstar

Capstar (nitenpyram) for Cats, Fast-Acting Oral Flea Treatment for Cats 2-25 lbs, Vet-Recommended Flea Medication Tablets Start Killing Fleas in 30 Minutes, 6 Doses

#7
Vet's Best

Vet's Best

Vet's Best Flea and Tick Home Spray | Flea Treatment for Dogs and Home | Plant-Based Formula | 32 Ounces, 2 Pack

#8
Cheristin

Cheristin

Cheristin Cat Cheristin Cat Flea Treatment & Prevention for Cats | 1 Topical Dose Provides Up to 6 Weeks of Coverage | 6 ct.

#9
Activate I

TevraPet

Activate II Flea and Tick Prevention for Dogs | 4 Count | Extra Large Dogs 55+ lbs | Topical Drops | 4 Months Flea Treatment

#10
Advantage

Advantage

Advantage II Small Cat Vet-Recommended Flea Treatment & Prevention | Cats 5-9 lbs. | 2-Month Supply

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