10 Best Stool Softener 2025 in the United States

The Amazon Basic Care ClearLax Polyethylene Glycol 3350 Powder is an osmotic laxative designed to relieve occasional constipation. Its active ingredient, Polyethylene Glycol 3350, is highly regarded and recommended by doctors, which is reassuring for those looking for a reliable stool softener. The product typically produces a bowel movement within 1 to 3 days, offering relief without urgent pressure.

One of its notable benefits is the ability to soften stools, making bowel movements more comfortable and frequent. The powder is unflavored, allowing it to be mixed into any beverage without altering the taste, which is convenient for those with taste sensitivities. Additionally, it is free from grit, sugar, and gluten, making it suitable for a variety of dietary needs.

The product is intended for adults and children aged 17 and older, which limits its use for younger children. As a part of Amazon's Basic Care line, it benefits from the brand's reputation for value and dependability. The product's size and weight make it easy to store and handle. While effective, it’s important to note that it might not be suitable for those looking for immediate relief due to its 1 to 3-day onset of action.

The Amazon Basic Care Stool Softener Laxative is designed to provide gentle and predictable relief from constipation. Each softgel contains 100 mg of docusate sodium, a commonly recommended active ingredient by physicians for stool softening. This product is effective for both adults and children aged 2 years and older, making it versatile for family use.

One of its significant strengths is the gentle action, typically producing results within 12 to 72 hours without harsh stimulants, which is beneficial for those looking for a mild and predictable solution to constipation. The product also stands out for being gluten-free, catering to individuals with gluten sensitivities. Additionally, its compact softgel form makes it easy to swallow, which is convenient for daily use.

On the downside, the onset of action can vary significantly, as it may take up to 72 hours for some users to experience relief. This variability might not be ideal for those seeking quicker results. Despite these minor drawbacks, this stool softener is a reliable option for those needing gentle constipation relief.

The Colace Regular Strength Stool Softener 100 mg Capsules offer gentle and dependable relief from occasional constipation. The active ingredient, docusate sodium, works by allowing water and fats to penetrate the stool, making it softer and easier to pass. This product is stimulant-free, which means it doesn't cause sudden bowel movements, making it a comfortable and safe choice for those who need relief without harsh side effects. Its onset of action ranges from 12 to 72 hours, which provides flexibility but might be slower for those seeking immediate relief.

The recommended usage is occasional, which aligns well with its gentle formulation, making it suitable for pregnant and postpartum women, although they should consult a health professional before use. Colace is a well-known and reputable brand, and being the #1 doctor-recommended stool softener adds to its credibility. However, while the product is effective for occasional use, it might not be ideal for chronic constipation sufferers who might need a faster-acting or more potent solution.

The capsules are a convenient dosage form, but some users may prefer other forms like liquid or chewable tablets. The product's safety and effectiveness make it a strong choice for those seeking gentle relief from occasional constipation.