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10 Best Topical Acne Products 2025 in the United States

From leading brands and best sellers available on the web.

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Differin A

Differin

13%OFF

Differin Acne Treatment Gel, 30 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Packaging May Vary)

#1

Winner

Differin A

Differin

Editor’s Choice

Differin Acne Treatment Gel, 30 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Packaging May Vary)

Sponsored

Differin A

Differin

13%OFF

Differin Acne Treatment Gel, 30 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Packaging May Vary)

#2
PanOxyl Ac

PanOxyl

PanOxyl Acne Foaming Wash Benzoyl Peroxide 10% Maximum Strength Antimicrobial, 5.5 Oz

#3
CeraVe Ret

CeraVe

CeraVe Retinol Serum for Post-Acne Marks and Skin Texture | Pore Refining, Resurfacing, Brightening Facial Serum with Retinol and Niacinamide | Fragrance Free, Paraben Free & Non-Comedogenic| 1 Oz

#4
La Roche-P

La Roche-Posay

La Roche-Posay Effaclar Dermatological 3 Step Acne Treatment System, Salicylic Acid Acne Cleanser, Pore Refining Toner, and Benzoyl Peroxide Spot Treatment for Sensitive Skin, 2-Month Supply

#5
Topicals F

Topicals

Topicals Faded Brightening and Clearing Serum | Reduces Discoloration, Post-Blemish Marks, Scars and Spots | Contains Kojic Acid and Niacinamide | Dermatologist-tested, Vegan, Cruelty-Free (0.5 Fl Oz)

#6
La Roche-P

La Roche-Posay

La Roche-Posay Effaclar Adapalene Gel 0.1% Acne Treatment | Retinoid Acne Cream | Acne Medication | Acne Gel For Blackheads & Whiteheads | Oil Free | Helps Clear And Prevent Acne & Clogged Pores

#7
CeraVe Acn

CeraVe

CeraVe Acne Control Gel, 2% Salicylic Acid Acne Treatment With Glycolic Acid + Lactic Acids + Niacniamide, Acne Gel Helps Clear Acne Blemishes Without Over Drying, Alcohol Free & Oil Free, 1.35 Fl Oz

#8
Proactiv E

Proactiv

Proactiv Emergency Blemish Relief - Benzoyl Peroxide Gel - Acne Spot Treatment for Face and Body, .33 Oz

#9
Amazon Bas

Amazon Basics

Amazon Basics Advanced Blemish Spot Treatment with 2% Salicylic Acid Acne Medication, 0.75 Fluid Ounces, 1-Pack

#10
De La Cruz

De La Cruz

De La Cruz Sulfur Ointment - Cystic Acne Treatment for Face and Body - Daily 10 Min Spot Treatment Mask - Safe and Effective Game Changing Hormonal Acne Treatment that Clears Up Pimples - 2.6 OZ Tube

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