10 Best Vertical Mouses 2025 in the United States

The J-Tech Digital Wired Ergonomic Vertical USB Mouse is designed with a focus on comfort and reducing strain, making it a good choice for users with carpal tunnel syndrome or those who spend long hours on the computer. Its ergonomic 'handshake' design is effective in minimizing wrist and arm stress, and the removable palm rest adds to the comfort level.

The mouse offers adjustable DPI settings (600/1000/1600), allowing users to customize the sensitivity based on their preference and tasks, which is a useful feature for both everyday use and light gaming or graphic work. Connectivity is straightforward with a USB connection, ensuring compatibility with most computers without the need for additional drivers. However, being wired may limit some users who prefer the freedom of a wireless setup.

The back/forward thumb buttons add convenience for web browsing and other repetitive tasks, and these buttons can be customized with third-party software for enhanced functionality. One notable downside is the need for a lithium-ion battery, even though it's rechargeable, which means you'll need to remember to keep it charged. In terms of compatibility, it works well with both Windows and Mac systems, making it a versatile option. Despite a few drawbacks, such as being wired and the need for charging, the J-Tech Digital V628 stands out for its ergonomic design and customization options.

The J-Tech Digital Scroll Endurance Wireless Mouse is designed with user comfort in mind, featuring a unique ergonomic design and a removable palm rest to reduce hand and wrist pain. This can be particularly beneficial for users who experience discomfort during extended computer use.

The mouse offers adjustable sensitivity with three DPI settings (600/1000/1600), making it suitable for various tasks, from casual browsing to precise work. The thumb buttons allow for convenient back/forward navigation in a browser, adding to its functionality. Connectivity is straightforward with its wireless USB technology and a nano receiver that can operate up to 10 meters away.

The product requires 2 AAA batteries, which may be a drawback for those preferring rechargeable options. Compatibility with various devices is assured, although it is not specified to support advanced customization software. Its size and weight make it portable, but some users might find it slightly bulky. This mouse is an excellent choice for individuals seeking an ergonomic vertical mouse to alleviate hand and wrist strain, provided that they are okay with its battery requirements and basic customization options.

The ASOYIOL Ergonomic Mouse Wireless is designed for users who need a comfortable and strain-free experience. Its vertical ergonomic design is beneficial for reducing hand strain and promoting healthier hand positioning, making it a good option for daily computer use and gaming. With adjustable DPI settings of 1000, 1200, and 1600, it allows for precise tracking on various surfaces, which is useful for both regular tasks and gaming.

The mouse features six buttons, including 'Page Back' and 'Page Forward' functionalities, catering to users who need extra buttons for navigation or gaming purposes. Connectivity is straightforward using a USB receiver, though it doesn't support MacOS X, limiting its compatibility to Windows and Linux systems. The built-in rechargeable battery is convenient and includes a power-saving mode after 8 minutes of inactivity, enhancing battery life.

The mouse is lightweight and portable, weighing only 3.35 ounces. If you're looking for an ergonomic mouse for Windows or Linux systems, this model is a solid choice, although Mac users will need to look elsewhere.