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10 Best Wrinkle Serum 2025 in the United States

From leading brands and best sellers available on the web.

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Obagi Medi

Obagi Medical

Obagi Medical ELASTIderm Facial Serum, 1.0 oz Pack of 2

#1

Winner

COSRX Snai

COSRX

COSRX Snail Mucin 96% Power Repairing Essence 3.38 fl.oz 100ml, Hydrating Serum for Face with Snail Secretion Filtrate for Dull Skin & Fine Lines, Korean Skin Care

Sponsored

Obagi Medi

Obagi Medical

Obagi Medical ELASTIderm Facial Serum, 1.0 oz Pack of 2

#2
TruSkin Vi

TruSkin

TruSkin Vitamin C Serum – Anti Aging Facial Serum with Vitamin C, Hyaluronic Acid, Vitamin E & More – Brightening Serum for Dark Spots, Even Skin Tone, Eye Area, Fine Lines & Wrinkles, 2 Fl Oz

#3
Vibriance

Vibriance

Vibriance Super C Serum for Mature Skin, Made in USA, All-In-One Formula Hydrates, Firms, Lifts, Smooths, Targets Age Spots, Wrinkles, Vitamin C Serum; 1 fl oz

#4
RoC Derm C

RoC

RoC Derm Correxion Advanced Retinol Firming Serum Stick with Antioxidants to Visibly Tighten and Firm Wrinkles and Laugh Lines, 1.0 oz with Retinol Eye Cream Packette

#5
Vitamin C

Eclat Skincare

Vitamin C Face Serum - Dark Spot Remover Facial Serum, Vit C Serum with Hyaluronic Acid, Ferulic Acid, & Vit E - Anti Aging and Skin Brightening Serum, Pure Vitamin C Serum Skin Care

#6
CeraVe Ant

CeraVe

CeraVe Anti Aging Retinol Serum | Cream Serum for Smoothing Fine Lines and Skin Brightening | With Retinol, Hyaluronic Acid, Niacinamide, and Ceramides | 1 Ounce

#7
SeoulCeuti

SeoulCeuticals

Editor’s Choice

SeoulCeuticals Korean Skin Care 20% Vitamin C Hyaluronic Acid Serum + CE Ferulic Acid - Potent Anti Aging, Anti Wrinkle Korean Beauty 1oz

#8
Premium 20

ELBBUB

Premium 20% Vitamin C Serum For Face with Hyaluronic Acid, Retinol & Amino Acids - Boost Skin Collagen,Hydrate & Plump Skin, Anti Aging & Wrinkle Facial Serum 60ml

#9
Good Molec

Good Molecules

Good Molecules Hyaluronic Acid Serum - Hydrating, Non-greasy formula to Moisturize, Plump - 1% HA, Anti-aging, Water-Based Skincare for Face

#10
Olay Super

Olay

Olay Super Serum 1.0 oz with Niacinamide, Vitamin C, Collagen Peptide, AHA, and Vitamin E

More products we considered

Collagen Serum For Face by Natural Outcome Skin Care - Ultra Impact Marine Collagen Peptides Serum for Face - Facial Moisturizer Anti Aging Serum Gel for Firming, Lifting and Reducing Wrinkles, 1 oz

Collagen Serum For Face by Natural Outcome Skin Care - Ultra Impact Marine Collagen Peptides Serum for Face - Facial Moisturizer Anti Aging Serum Gel for Firming, Lifting and Reducing Wrinkles, 1 oz

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Natural Outcome Mandelic Acid 10% | Anti-Aging AHA Facial Serum with Hyaluronic Acid | Targets Fine Lines, Dark Spots, and Wrinkles | Clarifies Acne and Stimulates Natural Collagen Production | 1 Oz

Natural Outcome Mandelic Acid 10% | Anti-Aging AHA Facial Serum with Hyaluronic Acid | Targets Fine Lines, Dark Spots, and Wrinkles | Clarifies Acne and Stimulates Natural Collagen Production | 1 Oz

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Pacifica Face Oil Serum - Flower Fix Bi-Phase Hydrating Skin Barrier - w/Hyaluronic Acid & Natural Botanical Ingredients - for Dry Sensitive Skin Vegan & Cruelty-Free Dermatologist Approved

Pacifica Face Oil Serum - Flower Fix Bi-Phase Hydrating Skin Barrier - w/Hyaluronic Acid & Natural Botanical Ingredients - for Dry Sensitive Skin Vegan & Cruelty-Free Dermatologist Approved

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Baebody Snail Mucin Serum Moisturizer - Hydrating Serum for Face with Collagen - Snail Mucin Moisturizer for Youthful Skin

Baebody Snail Mucin Serum Moisturizer - Hydrating Serum for Face with Collagen - Snail Mucin Moisturizer for Youthful Skin

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97% Snail Mucin Serum, Star Light by Zen Dew| Non-Sticky Snail Serum to Smooth, Brighten, Hydrate, Skin Repair |Cruelty Free, Made in S. Korea, 3.38 Fl Oz

97% Snail Mucin Serum, Star Light by Zen Dew| Non-Sticky Snail Serum to Smooth, Brighten, Hydrate, Skin Repair |Cruelty Free, Made in S. Korea, 3.38 Fl Oz

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