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10 Best Clean Clear Pimple Spot Treatments 2025 in the United States

From leading brands and best sellers available on the web.

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Differin A

Differin

34%OFF

Differin Acne Treatment Gel, 30 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Packaging May Vary)

#1

Winner

Daolyo Pim

Daolyo

Daolyo Pimple Patches for Face, 4 Size 300 Counts Acne Patches, Hydrocolloid Patches for Covering Zits and Blemishes, Spot Stickers with Salicylic Acid, Tea Tree Oil & Calendula Oil

Sponsored

Differin A

Differin

34%OFF

Differin Acne Treatment Gel, 30 Day Supply, Retinoid Treatment for Face with 0.1% Adapalene, Gentle Skin Care for Acne Prone Sensitive Skin, 15g Tube (Packaging May Vary)

#2
Murad Rapi

Murad

Murad Rapid Relief Acne Spot Treatment – Acne Control Max Strength 2% Salicylic Acid Invisible Gel Spot Solution for Fast Acne Relief - Reduces Blemish Size and Redness Within 4 Hours, 0.5 Oz

#3
Proactiv E

Proactiv

Proactiv Emergency Blemish Relief - Benzoyl Peroxide Gel - Acne Spot Treatment for Face and Body, .33 Oz

#4
Kate Somer

Kate Somerville

Kate Somerville EradiKate Acne Treatment - Clinically Formulated 10% Sulfur and BHA Spot Treatment – Clears Pimples, Cleans Pores and Prevents Breakouts, 1 Fl Oz

#5
Amazon Bas

Amazon Basics

Amazon Basics Advanced Blemish Spot Treatment with 2% Salicylic Acid Acne Medication, 0.75 Fluid Ounces, 1-Pack

#6
Kiehl's Tr

Kiehl's

Kiehl's Truly Targeted Acne-Clearing Pimple Patch with 2% Salicylic Acid, Invisible Liquid Acne Spot Treatment, 4% Niacinamide Fades Post-acne Marks, 0.2% Licorice Root Soothes Redness - 0.5 fl oz

#7
Dermalogic

Dermalogica

Dermalogica Clear Start Breakout Clearing Booster (1 Fl Oz) Acne Spot Treatment with Salicylic Acid - Clears Breakouts & Locks in Moisture To Soothe Irritation

#8
Almay Clea

Almay

Almay Clear Complexion Acne & Blemish Spot Treatment Concealer Makeup with Salicylic Acid- Lightweight, Full Coverage, Hypoallergenic, Fragrance-Free, for Sensitive Skin, 050 Fair, 0.3 fl oz.

#9
Bliss Clea

Bliss

Editor’s Choice

Bliss Clear Genius Acne Spot Treatment – Maximum Strength 2% Salicylic Acid Shrinks Blemishes – Clean, Vegan, Cruelty-Free, 0.5 Fl Oz

#10
AcneFree T

AcneFree

AcneFree Terminator 10 Acne Spot Treatment with Benzoyl Peroxide 10% Maximum Strength Acne Cream Treatment, 1 Ounce - Pack Of 1

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