We Use CookiesWe use cookies to enhance the security, performance, functionality and for analytical and promotional activities. By continuing to browse this site you are agreeing to our privacy policy

All Categories

Health & Household

Health Care

Cold And Flu Medicines

10 Best Cold And Flu Medicines 2025 in the United States

Name: Vicks DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, & Cough, 48ct
Brand: Vicks
Price: 16.97 USD
Availability: InStock

From leading brands and best sellers available on the web.

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

View on Amazon

Winner

Vicks

Vicks DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, & Cough, 48ct

9.9

score

View on Amazon

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

View on Amazon

Tylenol

Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count

9.8

score

View on Amazon

Zicam

Zicam Cold Remedy Zinc RapidMelts, Elderberry Citrus Flavor, Homeopathic, Cold Shortening Medicine, Shortens Cold Duration, 25 Count

9.7

score

View on Amazon

Vicks

Vicks NyQuil SEVERE Cold, Flu, and Congestion Medicine, 2x12 fl oz Twin Pack, Berry Flavor, Maximum Strength, Nighttime Relief

9.5

score

View on Amazon

Zicam

Zicam Cold Remedy Cold Shortening Medicated Nasal Swabs Zinc-Free 20ct

9.3

score

View on Amazon

Vicks

Vicks DayQuil & NyQuil Co-Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime & Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, & Cough, 72ct

9.1

score

View on Amazon

Mucinex

Mucinex FastMax DM Max Cold & Flu Liquid - Thins Mucus, Relieves Cough, Chest Congestion, Pain, Fever, Sneezing, Sore Throat, Runny Nose

8.9

score

View on Amazon

Mucinex

Mucinex Fast-Max Cold and Flu & Nightshift Severe Cold and Flu Medicine for Adults, Over-the-Counter Medication Combo Pack for Sore Throat Relief, Decongestant, Cough & Cold Medicines, 2 x 6 Fl Oz

8.6

score

View on Amazon

Zicam

Zicam Cold Remedy No-Drip Nasal Spray with Cooling Menthol & Eucalyptus, Homeopathic, Zinc-Free, Pre-Cold Medicine, Shortens Cold Duration, 0.5 Ounce

8.4

score

View on Amazon

#10

Mucinex

Mucinex Fast-Max Day Cold and Flu & Night Cold and Flu Medicine for Adults, Day/Night Combo Pack for Fever, Sore Throat Relief, Decongestant, Cough & Cold Medicines, 24 Fast-Dissolving Liquid Gels

8.2

score

View on Amazon

More products we considered

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

View Deal

Herbion Naturals Cough Drops - Honey Lemon Flavor, Soothing Dietary Supplement for Adults & Children (6+), 18 Drops, No Artificial Flavors or Colors

View Deal

HealthA2Z® Daytime and Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (24 Daytime & 12 Nighttime Softgels) (Daytime & Nighttime Combo (36 Count Pack of 1))

View Deal

HealthA2Z® Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (20 Softgels) (20 Softgels)

View Deal

HealthA2Z® Daytime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime(20 Softgels) (Daytime Cold & Flu Medicine (20 Count Pack of 1))

View Deal

How do we rank products for you?

Our technology thoroughly searches through the online shopping world, reviewing hundreds of sites. We then process and analyze this information, updating in real-time to bring you the latest top-rated products. This way, you always get the best and most current options available.

10 Best Cold And Flu Medicines 2025 in the United States

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

Vicks DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, & Cough, 48ct

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count

Zicam Cold Remedy Zinc RapidMelts, Elderberry Citrus Flavor, Homeopathic, Cold Shortening Medicine, Shortens Cold Duration, 25 Count

Vicks NyQuil SEVERE Cold, Flu, and Congestion Medicine, 2x12 fl oz Twin Pack, Berry Flavor, Maximum Strength, Nighttime Relief

Zicam Cold Remedy Cold Shortening Medicated Nasal Swabs Zinc-Free 20ct

Vicks DayQuil & NyQuil Co-Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime & Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, & Cough, 72ct

Mucinex FastMax DM Max Cold & Flu Liquid - Thins Mucus, Relieves Cough, Chest Congestion, Pain, Fever, Sneezing, Sore Throat, Runny Nose

Mucinex Fast-Max Cold and Flu & Nightshift Severe Cold and Flu Medicine for Adults, Over-the-Counter Medication Combo Pack for Sore Throat Relief, Decongestant, Cough & Cold Medicines, 2 x 6 Fl Oz

Zicam Cold Remedy No-Drip Nasal Spray with Cooling Menthol & Eucalyptus, Homeopathic, Zinc-Free, Pre-Cold Medicine, Shortens Cold Duration, 0.5 Ounce

Mucinex Fast-Max Day Cold and Flu & Night Cold and Flu Medicine for Adults, Day/Night Combo Pack for Fever, Sore Throat Relief, Decongestant, Cough & Cold Medicines, 24 Fast-Dissolving Liquid Gels

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

Herbion Naturals Cough Drops - Honey Lemon Flavor, Soothing Dietary Supplement for Adults & Children (6+), 18 Drops, No Artificial Flavors or Colors

HealthA2Z® Daytime and Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (24 Daytime & 12 Nighttime Softgels) (Daytime & Nighttime Combo (36 Count Pack of 1))

HealthA2Z® Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (20 Softgels) (20 Softgels)

HealthA2Z® Daytime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime(20 Softgels) (Daytime Cold & Flu Medicine (20 Count Pack of 1))

FAQ

What is the best over-the-counter medicine for cold and flu?

How do cold and flu medicines work?

What are the side effects of common cold and flu medications?

Can you take cold and flu medicine while pregnant or breastfeeding?

What are the differences between daytime and nighttime cold and flu medications?

10 Best Cold And Flu Medicines 2025 in the United States

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

Vicks DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, & Cough, 48ct

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count

Zicam Cold Remedy Zinc RapidMelts, Elderberry Citrus Flavor, Homeopathic, Cold Shortening Medicine, Shortens Cold Duration, 25 Count

Vicks NyQuil SEVERE Cold, Flu, and Congestion Medicine, 2x12 fl oz Twin Pack, Berry Flavor, Maximum Strength, Nighttime Relief

Zicam Cold Remedy Cold Shortening Medicated Nasal Swabs Zinc-Free 20ct

Hyland's Kids Nighttime Organic Cough Syrup & Immune Support with Agave, Elderberry & Pomegranate - Soothes Cough and Cold, & Supports Immunity - 4 Fl. Oz.

Hyland's Naturals Baby Mucus and Cold Relief, Daytime Baby Cold Medicine, Infant Cold and Cough Remedy, Decongestant, 4 Fluid Ounce (Pack of 2)

Hyland's Baby Organic Cough & Immune Day & Night Combo Pack, Eases Coughs, Supports Immunity, Promotes Sleep + Chest Rub, Soothe & Comfort Organic Lavender, Peppermint, & Chamomile Flower Oil

Herbion Naturals Respiratory Care Herbal Granules with Natural Lemon Flavor–10 Ct, for The Whole Family –Healthy Respiratory Function-Relieves Cough

Herbion Naturals Respiratory Care Herbal Granules – 10 Ct for The Whole Family – Promotes Healthy Nasal Passages & Respiratory Function - Relieves Cold and Flu Symptoms – Supports Immune System

Vicks DayQuil & NyQuil Co-Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime & Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, & Cough, 72ct

Mucinex FastMax DM Max Cold & Flu Liquid - Thins Mucus, Relieves Cough, Chest Congestion, Pain, Fever, Sneezing, Sore Throat, Runny Nose

Mucinex Fast-Max Cold and Flu & Nightshift Severe Cold and Flu Medicine for Adults, Over-the-Counter Medication Combo Pack for Sore Throat Relief, Decongestant, Cough & Cold Medicines, 2 x 6 Fl Oz

Zicam Cold Remedy No-Drip Nasal Spray with Cooling Menthol & Eucalyptus, Homeopathic, Zinc-Free, Pre-Cold Medicine, Shortens Cold Duration, 0.5 Ounce

Mucinex Fast-Max Day Cold and Flu & Night Cold and Flu Medicine for Adults, Day/Night Combo Pack for Fever, Sore Throat Relief, Decongestant, Cough & Cold Medicines, 24 Fast-Dissolving Liquid Gels

Flu Medicines

Cold Flu Medicines

Medicines Colds

Baby Cough And Cold Medicines

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

Herbion Naturals Cough Drops - Honey Lemon Flavor, Soothing Dietary Supplement for Adults & Children (6+), 18 Drops, No Artificial Flavors or Colors

HealthA2Z® Daytime and Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (24 Daytime & 12 Nighttime Softgels) (Daytime & Nighttime Combo (36 Count Pack of 1))

HealthA2Z® Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (20 Softgels) (20 Softgels)

HealthA2Z® Daytime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime(20 Softgels) (Daytime Cold & Flu Medicine (20 Count Pack of 1))

FAQ

What is the best over-the-counter medicine for cold and flu?

How do cold and flu medicines work?

What are the side effects of common cold and flu medications?

Can you take cold and flu medicine while pregnant or breastfeeding?

What are the differences between daytime and nighttime cold and flu medications?