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Cold Flu Medicines

10 Best Cold Flu Medicines 2025 in the United States

Name: Vicks DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, & Cough, 48ct
Brand: Vicks
Price: 16.97 USD
Availability: InStock

From leading brands and best sellers available on the web.

Kids Cold Medicine for Ages 2+, Hyland's Naturals Kids Cold & Cough, Day and Night Value Pack, Grape Syrup, Cough Medicine for Kids, 4 Fl Oz Each, 2 Count (Pack of 1)

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Winner

Vicks

Vicks DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, & Cough, 48ct

10.0

score

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Kids Cold Medicine for Ages 2+, Hyland's Naturals Kids Cold & Cough, Day and Night Value Pack, Grape Syrup, Cough Medicine for Kids, 4 Fl Oz Each, 2 Count (Pack of 1)

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Tylenol

Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count

10.0

score

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Vicks

Vicks NyQuil SEVERE Cold, Flu, and Congestion Medicine, 2x12 fl oz Twin Pack, Berry Flavor, Maximum Strength, Nighttime Relief

9.8

score

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Mucinex

Mucinex FastMax DM Max Cold & Flu Liquid - Thins Mucus, Relieves Cough, Chest Congestion, Pain, Fever, Sneezing, Sore Throat, Runny Nose

9.6

score

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Vicks

Vicks DayQuil & NyQuil Co-Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime & Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, & Cough, 72ct

9.4

score

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Amazon Basic Care

Amazon Basic Care Nighttime Severe Cold and Flu Syrup, Max Strength Liquid Medicine, Multi-Symptom Relief, for Adults and Children 12 Years and Older, Mixed Berry Flavor, 12 fl oz (Pack of 1)

9.1

score

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Mucinex

Mucinex Fast-Max Cold and Flu & Nightshift Severe Cold and Flu Medicine for Adults, Over-the-Counter Medication Combo Pack for Sore Throat Relief, Decongestant, Cough & Cold Medicines, 2 x 6 Fl Oz

8.9

score

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ALKA-SELTZER PLUS

ALKA-SELTZER PLUS Cold & Flu Medicine for Nasal Congestion, Cough, Fever - Citrus, 48ct

8.7

score

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Vicks

Vicks DayQuil & NyQuil SEVERE Honey Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, & Cough, Honey Flavor, 2x12 OZ

8.4

score

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#10

Amazon Basic Care

Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count

8.2

score

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More products we considered

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

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Herbion Naturals Cough Drops - Honey Lemon Flavor, Soothing Dietary Supplement for Adults & Children (6+), 18 Drops, No Artificial Flavors or Colors

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HealthA2Z® Daytime and Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (24 Daytime & 12 Nighttime Softgels) (Daytime & Nighttime Combo (36 Count Pack of 1))

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HealthA2Z® Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (20 Softgels) (20 Softgels)

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HealthA2Z® Daytime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime(20 Softgels) (Daytime Cold & Flu Medicine (20 Count Pack of 1))

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How do we rank products for you?

Our technology thoroughly searches through the online shopping world, reviewing hundreds of sites. We then process and analyze this information, updating in real-time to bring you the latest top-rated products. This way, you always get the best and most current options available.

10 Best Cold Flu Medicines 2025 in the United States

Kids Cold Medicine for Ages 2+, Hyland's Naturals Kids Cold & Cough, Day and Night Value Pack, Grape Syrup, Cough Medicine for Kids, 4 Fl Oz Each, 2 Count (Pack of 1)

Vicks DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, & Cough, 48ct

Kids Cold Medicine for Ages 2+, Hyland's Naturals Kids Cold & Cough, Day and Night Value Pack, Grape Syrup, Cough Medicine for Kids, 4 Fl Oz Each, 2 Count (Pack of 1)

Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count

Vicks NyQuil SEVERE Cold, Flu, and Congestion Medicine, 2x12 fl oz Twin Pack, Berry Flavor, Maximum Strength, Nighttime Relief

Mucinex FastMax DM Max Cold & Flu Liquid - Thins Mucus, Relieves Cough, Chest Congestion, Pain, Fever, Sneezing, Sore Throat, Runny Nose

Vicks DayQuil & NyQuil Co-Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime & Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, & Cough, 72ct

Amazon Basic Care Nighttime Severe Cold and Flu Syrup, Max Strength Liquid Medicine, Multi-Symptom Relief, for Adults and Children 12 Years and Older, Mixed Berry Flavor, 12 fl oz (Pack of 1)

Mucinex Fast-Max Cold and Flu & Nightshift Severe Cold and Flu Medicine for Adults, Over-the-Counter Medication Combo Pack for Sore Throat Relief, Decongestant, Cough & Cold Medicines, 2 x 6 Fl Oz

ALKA-SELTZER PLUS Cold & Flu Medicine for Nasal Congestion, Cough, Fever - Citrus, 48ct

Vicks DayQuil & NyQuil SEVERE Honey Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, & Cough, Honey Flavor, 2x12 OZ

Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

Herbion Naturals Cough Drops - Honey Lemon Flavor, Soothing Dietary Supplement for Adults & Children (6+), 18 Drops, No Artificial Flavors or Colors

HealthA2Z® Daytime and Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (24 Daytime & 12 Nighttime Softgels) (Daytime & Nighttime Combo (36 Count Pack of 1))

HealthA2Z® Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (20 Softgels) (20 Softgels)

HealthA2Z® Daytime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime(20 Softgels) (Daytime Cold & Flu Medicine (20 Count Pack of 1))

FAQ

What are the best over-the-counter medicines for the flu?

What are the differences between cold and flu medicines?

What are the side effects of common cold and flu medications?

What cold and flu medicines are safe for children?

Are there any natural remedies that can help with cold and flu symptoms?

10 Best Cold Flu Medicines 2025 in the United States

Kids Cold Medicine for Ages 2+, Hyland's Naturals Kids Cold & Cough, Day and Night Value Pack, Grape Syrup, Cough Medicine for Kids, 4 Fl Oz Each, 2 Count (Pack of 1)

Vicks DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, & Cough, 48ct

Kids Cold Medicine for Ages 2+, Hyland's Naturals Kids Cold & Cough, Day and Night Value Pack, Grape Syrup, Cough Medicine for Kids, 4 Fl Oz Each, 2 Count (Pack of 1)

Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count

Vicks NyQuil SEVERE Cold, Flu, and Congestion Medicine, 2x12 fl oz Twin Pack, Berry Flavor, Maximum Strength, Nighttime Relief

Mucinex FastMax DM Max Cold & Flu Liquid - Thins Mucus, Relieves Cough, Chest Congestion, Pain, Fever, Sneezing, Sore Throat, Runny Nose

Vicks DayQuil & NyQuil Co-Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime & Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, & Cough, 72ct

Hyland's - Kids - Organic Cough & Immune Day & Night Combo Pack - Eases Coughs, Supports Immunity, Promotes Sleep, Two 4 Fl Oz. Bottles (8 fl oz) (Pack of 2)

Hyland's Naturals Baby Mucus and Cold Relief, Daytime Baby Cold Medicine, Infant Cold and Cough Remedy, Decongestant, 4 Fluid Ounce (Pack of 2)

Hyland's Baby Organic Cough & Immune Day & Night Combo Pack, Eases Coughs, Supports Immunity, Promotes Sleep + Chest Rub, Soothe & Comfort Organic Lavender, Peppermint, & Chamomile Flower Oil

Herbion Naturals Respiratory Care Herbal Granules with Natural Lemon Flavor–10 Ct, for The Whole Family –Healthy Respiratory Function-Relieves Cough

Herbion Naturals Respiratory Care Herbal Granules – 10 Ct for The Whole Family – Promotes Healthy Nasal Passages & Respiratory Function - Relieves Cold and Flu Symptoms – Supports Immune System

Amazon Basic Care Nighttime Severe Cold and Flu Syrup, Max Strength Liquid Medicine, Multi-Symptom Relief, for Adults and Children 12 Years and Older, Mixed Berry Flavor, 12 fl oz (Pack of 1)

Mucinex Fast-Max Cold and Flu & Nightshift Severe Cold and Flu Medicine for Adults, Over-the-Counter Medication Combo Pack for Sore Throat Relief, Decongestant, Cough & Cold Medicines, 2 x 6 Fl Oz

ALKA-SELTZER PLUS Cold & Flu Medicine for Nasal Congestion, Cough, Fever - Citrus, 48ct

Vicks DayQuil & NyQuil SEVERE Honey Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, & Cough, Honey Flavor, 2x12 OZ

Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count

Cold And Flu Medicines

Flu Medicines

Medicines Colds

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

Herbion Naturals Cough Drops - Honey Lemon Flavor, Soothing Dietary Supplement for Adults & Children (6+), 18 Drops, No Artificial Flavors or Colors

HealthA2Z® Daytime and Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (24 Daytime & 12 Nighttime Softgels) (Daytime & Nighttime Combo (36 Count Pack of 1))

HealthA2Z® Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (20 Softgels) (20 Softgels)

HealthA2Z® Daytime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime(20 Softgels) (Daytime Cold & Flu Medicine (20 Count Pack of 1))

FAQ

What are the best over-the-counter medicines for the flu?

What are the differences between cold and flu medicines?

What are the side effects of common cold and flu medications?

What cold and flu medicines are safe for children?

Are there any natural remedies that can help with cold and flu symptoms?