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10 Best Pain Reliever For Headache 2025 in the United States

From leading brands and best sellers available on the web.

Sponsored

Magic Gel

Magic Gel

Magic Gel Migraine Ice Head Wrap | Real Migraine & Headache Relief | The Original Headache Cap | Cold, Comfortable, Dark & Cool; Endorsed by Physicians, Loved by Thousands (Purple)

#1

Winner

Tylenol Ex

Tylenol

Tylenol Extra Strength Acetaminophen Rapid Release Gels, Pain Reliever & Fever Reducer, 100 ct

Sponsored

Magic Gel

Magic Gel

Magic Gel Migraine Ice Head Wrap | Real Migraine & Headache Relief | The Original Headache Cap | Cold, Comfortable, Dark & Cool; Endorsed by Physicians, Loved by Thousands (Purple)

#2
Amazon Bas

Amazon Basic Care

Amazon Basic Care Ibuprofen Tablets 200 mg, Pain Reliever/Fever Reducer, Body Aches, Headache, Arthritis Pain Relief and More, 500 Count (Pack of 1)

#3
Tylenol Ex

Tylenol

Tylenol Extra Strength Caplets with 500 mg Acetaminophen, Pain Reliever and Fever Reducer for Headache, Backache, Toothache & Minor Arthritis Pain Relief, 100 Count

#4
Amazon Bas

Amazon Basic Care

Amazon Basic Care Naproxen Sodium Tablets 220 mg, Pain Reliever/Fever Reducer (NSAID), Muscular Aches, Backache, Headache, Toothache, Minor Arthritis Pain Relief and More, 300 Count

#5
Excedrin E

Excedrin

Excedrin Extra Strength Pain Relief Caplets For Headache Relief, Temporarily Relieves Minor Aches And Pains Due To Headache - 200 Count

#6
Goody's Ex

Goody's

Goody's Extra Strength Headache Powder, Cool Orange Flavor Dissolve Packs, 24 Individual Packets (2 Pack)

#7
Amazon Bas

Amazon Basic Care

Amazon Basic Care Children's Dye-Free Pain and Fever, Acetaminophen 160 mg per 5 mL Oral Suspension, Cherry Flavor, Fever Reducer and Pain Reliever for Headache, Sore Throat and Toothache, 8 fl oz

#8
GenCare -

GenCare

GenCare - Headache Relief Acetaminophen with Aspirin (NSAID) & Caffeine (300 Caplets) Value Pack | Head Pain, Muscle Aches, Back Pain & Body | Generic Excedrin Extra Strength

#9
Excedrin T

Excedrin

Excedrin Tension Headache Relief Caplets Without Aspirin for Head, Neck and Shoulder Pain Relief - 100 Count

#10
Excedrin P

Excedrin

Excedrin PM Sleep Aid with Headache Relief Caplets for Nighttime Headaches and Sleeplessness - 100 Count

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