We Use CookiesWe use cookies to enhance the security, performance, functionality and for analytical and promotional activities. By continuing to browse this site you are agreeing to our privacy policy

10 Best Puppy Urine Cleaner 2025 in the United States

How do we rank products for you?

Our technology thoroughly searches through the online shopping world, reviewing hundreds of sites. We then process and analyze this information, updating in real-time to bring you the latest top-rated products. This way, you always get the best and most current options available.

headphones-stars

Our Top Picks

#1

Winner

Rocco & Roxie Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray

Rating
9.7
Chosen by1,213
Enzyme-based formula
Scent
Surface compatibility

Most important from
118954 reviews

Enzyme-based formula
Even stubborn, long-standing odors were completely eradicated, something other cleaners failed to achieve.
Scent
The pleasant, non-chemical scent is a bonus, making the house smell fresh without being overpowering.
Surface compatibility
It's highly effective on various surfaces, including carpets, hardwood, and fabric, without leaving any residue.
Speed of action
This cleaner is a miracle worker! It eliminated stains and odors instantly, making it seem like the mess was never there.
Safety for pets and children
The product is safe for pets and children, with no harsh chemicals, which is a huge relief for pet owners.
Ease of use
Using this cleaner has prevented pets from returning to the same spots, breaking the cycle of re-marking.

Rocco & Roxie Stain & Odor Eliminator is an enzyme-based cleaner designed to tackle tough stains and odors, including puppy urine. Its formula is activated upon contact, breaking down ammonia crystals and organic matter effectively. This makes it highly efficient in removing not just the stains but also the lingering smells. The product is versatile, suitable for use on various surfaces like carpets, floors, furniture, and even pet bedding, which is a significant advantage for households with pets.

Additionally, it's certified safe for pets and children, chlorine-free, and color-safe, ensuring it leaves no harmful residue behind, making it trustworthy for pet owners. Its original scent is pleasant, though some users might prefer a fragrance-free option. The speed of action is commendable, efficiently dealing with fresh stains and odors, although older, set-in stains might require repeated applications.

The spray form facilitates easy application, but handling larger spills might take more effort. While the cleaner is generally praised, it's important to buy it from authorized sellers to ensure satisfaction because the manufacturer’s satisfaction guarantee does not apply to purchases from unauthorized sellers. This product is particularly beneficial for pet owners seeking a safe, effective, and easy-to-use solution for maintaining a clean and fresh home environment.

Rating
9.7
Chosen by1,213
Enzyme-based formula
Scent
Surface compatibility

Most important from
118954 reviews

Enzyme-based formula
Even stubborn, long-standing odors were completely eradicated, something other cleaners failed to achieve.
Scent
The pleasant, non-chemical scent is a bonus, making the house smell fresh without being overpowering.
Surface compatibility
It's highly effective on various surfaces, including carpets, hardwood, and fabric, without leaving any residue.
Speed of action
This cleaner is a miracle worker! It eliminated stains and odors instantly, making it seem like the mess was never there.
Safety for pets and children
The product is safe for pets and children, with no harsh chemicals, which is a huge relief for pet owners.
Ease of use
Using this cleaner has prevented pets from returning to the same spots, breaking the cycle of re-marking.
#2

Angry Orange Pet Odor Eliminator for Home - 8oz Dog and Cat Pee Smell Remover for Carpet, Grass, Tile and Furniture - Citrus Concentrate, Makes 128oz of Liquid

Rating
9.4
Scent
Surface compatibility

Most important from
75419 reviews

Scent
The citrus scent is strong and can be overwhelming without proper ventilation, but it effectively masks and removes pet urine odors.
Surface compatibility
This product is a miracle liquid gold that permanently eliminated severe cat urine odors from floorboards and walls.

The Angry Orange Pet Odor Eliminator is an enzyme-based formula designed to tackle tough pet urine odors effectively. Its enzymes work to break down the odor-causing proteins, ensuring the smells don’t return, which is a crucial feature for anyone dealing with persistent pet accidents. The product has a pleasant citrus scent derived from orange peels, leaving your home smelling fresh and inviting. This scent can be a significant advantage for those who prefer a natural aroma over chemical smells.

The concentrate makes up to 128 ounces of cleaning solution, which means a small 8oz bottle can go a long way, providing value for money. The cleaner is versatile and can be used on various surfaces including carpet, tile, wood, and grass, making it a handy tool for different cleaning needs around the home. However, it should not be used on leather, which can be a limitation for some users.

The product is manual and easy to use; simply dilute the concentrate in water, shake, and spray where needed. Safety is another strong point—being pet-friendly and non-toxic, it offers peace of mind to pet owners. The only potential drawbacks include the initial preparation step, which requires mixing the concentrate with water, and the limitation regarding leather surfaces. Nonetheless, its effectiveness, pleasant scent, and safety features make it a good choice for households with pets.

Rating
9.4
Scent
Surface compatibility

Most important from
75419 reviews

Scent
The citrus scent is strong and can be overwhelming without proper ventilation, but it effectively masks and removes pet urine odors.
Surface compatibility
This product is a miracle liquid gold that permanently eliminated severe cat urine odors from floorboards and walls.
#3

Angry Orange Stain Remover - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies

Rating
9.1
Enzyme-based formula
Scent
Surface compatibility

Most important from
28384 reviews

Enzyme-based formula
This enzyme cleaner is incredibly versatile, working on carpets, floors, upholstery, and more.
Scent
The citrus scent is a refreshing change from typical cleaners and helps mask pet odors effectively.
Surface compatibility
This enzyme cleaner is incredibly versatile, working on carpets, floors, upholstery, and more.
Speed of action
While it works great on new stains, older fabric stains may not be completely removed, which is expected for set-in stains.
Safety for pets and children
The product is safe for pets and children, making it a reliable choice for households with multiple pets.
Ease of use
The application is straightforward: spray, wipe, and let dry, with no need for dilution.

The Angry Orange Stain Remover stands out with its enzyme-based formula, which is effective in breaking down and eliminating pet stains and odors from urine, feces, and vomit. This makes it a strong choice for pet owners dealing with persistent messes. Its citrus scent not only freshens up the area but also helps in making the cleaning process more pleasant.

The product is multipurpose and can be used on various surfaces including carpets, tiles, hardwood, upholstery, car interiors, and even artificial turf. This versatility makes it a practical solution for different cleaning needs around the house. One of its key advantages is its safety for pets and children, which is crucial for households with young kids and multiple pets. Additionally, the spray form makes it easy to apply, and the directions for use are straightforward, ensuring that users can achieve the best results with minimal effort.

However, the product does have some drawbacks. The speed of action may vary depending on the severity of the stain and the surface type, meaning it might require multiple applications for tougher stains. Also, the strong citrus scent, while pleasant for some, might be overwhelming for others. The Angry Orange Stain Remover is a versatile and effective enzyme cleaner suitable for pet owners looking to tackle a variety of stains and odors safely and efficiently.

Rating
9.1
Enzyme-based formula
Scent
Surface compatibility

Most important from
28384 reviews

Enzyme-based formula
This enzyme cleaner is incredibly versatile, working on carpets, floors, upholstery, and more.
Scent
The citrus scent is a refreshing change from typical cleaners and helps mask pet odors effectively.
Surface compatibility
This enzyme cleaner is incredibly versatile, working on carpets, floors, upholstery, and more.
Speed of action
While it works great on new stains, older fabric stains may not be completely removed, which is expected for set-in stains.
Safety for pets and children
The product is safe for pets and children, making it a reliable choice for households with multiple pets.
Ease of use
The application is straightforward: spray, wipe, and let dry, with no need for dilution.

Buying Guide for the Best Puppy Urine Cleaner

Choosing the right puppy urine cleaner is essential for maintaining a clean and odor-free home. Puppies are prone to accidents, and having an effective cleaner can make the cleanup process much easier and more efficient. When selecting a puppy urine cleaner, consider the following key specifications to ensure you pick the best product for your needs.
Enzyme-based formulaAn enzyme-based formula is important because it breaks down the proteins in urine, effectively eliminating odors and stains. Enzymes are biological molecules that speed up chemical reactions, making them highly effective at cleaning organic messes like urine. Look for cleaners that specifically mention enzymes on the label. If you have a puppy that frequently has accidents, an enzyme-based cleaner is a must-have to ensure thorough cleaning and odor removal.
ScentThe scent of the cleaner can be important for both you and your puppy. Some cleaners have strong fragrances that can mask odors, while others are unscented. If you or your puppy are sensitive to strong smells, opt for an unscented or lightly scented cleaner. On the other hand, if you prefer a fresh-smelling home, choose a cleaner with a pleasant fragrance. Your personal preference and sensitivity to scents should guide your choice here.
Surface compatibilitySurface compatibility refers to the types of surfaces the cleaner can be used on, such as carpets, hardwood floors, tiles, and upholstery. It's important to choose a cleaner that is safe and effective on the surfaces in your home. Check the label to ensure the cleaner is suitable for the specific areas where your puppy has accidents. If your puppy tends to urinate on a variety of surfaces, look for a versatile cleaner that works on multiple types of materials.
Speed of actionThe speed of action indicates how quickly the cleaner works to remove stains and odors. Some cleaners require a longer time to sit and break down the urine, while others act more quickly. If you need a fast solution for immediate cleanup, choose a cleaner with a quick action time. However, if you can afford to let the cleaner sit for a while, a slower-acting cleaner might be just as effective. Consider your typical cleanup routine and how quickly you need results.
Safety for pets and childrenSafety is crucial when choosing a cleaner, especially if you have pets and children in the home. Ensure the cleaner is non-toxic and safe for use around animals and kids. Look for labels that mention pet-safe or child-safe ingredients. If your puppy or children frequently come into contact with cleaned areas, prioritize safety to avoid any harmful effects. Your household's safety should be a top priority in your decision-making process.
Ease of useEase of use refers to how simple and convenient the cleaner is to apply. Some cleaners come in spray bottles, while others may require mixing with water. Choose a cleaner that fits your preferred method of application. If you prefer a quick and easy cleanup, a spray bottle might be more convenient. If you don't mind a bit of preparation, other forms might be suitable. Your preference for convenience and ease should guide your choice.

FAQ

Most Popular Categories Right Now