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10 Best Wrinkle Serums 2025 in the United States

From leading brands and best sellers available on the web.

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Obagi Medi

Obagi Medical

Obagi Medical ELASTIderm Facial Serum, 1.0 oz Pack of 2

#1

Winner

COSRX Snai

COSRX

COSRX Snail Mucin 96% Power Repairing Essence 3.38 fl.oz 100ml, Hydrating Serum for Face with Snail Secretion Filtrate for Dull Skin & Fine Lines, Korean Skin Care

Sponsored

Obagi Medi

Obagi Medical

Obagi Medical ELASTIderm Facial Serum, 1.0 oz Pack of 2

#2
TruSkin Vi

TruSkin Naturals

TruSkin Vitamin C Serum – Anti Aging Facial Serum with Vitamin C, Hyaluronic Acid, Vitamin E & More – Brightening Serum for Dark Spots, Even Skin Tone, Eye Area, Fine Lines & Wrinkles, 1 Fl Oz

#3
Beauty of

Beauty of Joseon

Beauty of Joseon Revive Eye Serum with Retinal Niacinamide Correction for Puffy Eye Bags Fine Lines Dark Circles Wrinkles, Korean Skin Care 30ml, 1 fl.oz

#4
Vibriance

Vibriance

Vibriance Super C Serum for Mature Skin, Made in USA, All-In-One Formula Hydrates, Firms, Lifts, Smooths, Targets Age Spots, Wrinkles, Vitamin C Serum; 1 fl oz

#5
RoC Derm C

RoC

RoC Derm Correxion Advanced Retinol Firming Serum Stick with Antioxidants to Visibly Tighten and Firm Wrinkles and Laugh Lines, 1.0 oz with Retinol Eye Cream Packette

#6
Bliss Yout

Bliss

Editor’s Choice

Bliss Youth Got This Retinol Serum | Advanced Anti-Aging Formula | Reduces Fine Lines & Wrinkles | Dermatologist-Tested | Clinically Proven Results | Fragrance-Free & Vegan | 0.67 Fl Oz |

#7
CeraVe Ant

CeraVe

CeraVe Anti Aging Retinol Serum | Cream Serum for Smoothing Fine Lines and Skin Brightening | With Retinol, Hyaluronic Acid, Niacinamide, and Ceramides | 1 Ounce

#8
RoC Multi

RoC

RoC Multi Correxion Revive + Glow 10% Active Vitamin C Serum for Face, Daily Anti-Aging Wrinkle and Skin Tone Skin Care Treatment, Brightening Serum, 1 Fluid Ounce

#9
L'Oreal Pa

L’Oréal Paris

L'Oreal Paris Revitalift 1.5% Pure Hyaluronic Acid Face Serum, Hydrate & Reduce Wrinkles, Fragrance Free 1 oz

#10
Good Molec

Good Molecules

Good Molecules Hyaluronic Acid Serum - Hydrating, Non-greasy formula to Moisturize, Plump - 1% HA, Anti-aging, Water-Based Skincare for Face

More products we considered

Collagen Serum For Face by Natural Outcome Skin Care - Ultra Impact Marine Collagen Peptides Serum for Face - Facial Moisturizer Anti Aging Serum Gel for Firming, Lifting and Reducing Wrinkles, 1 oz

Collagen Serum For Face by Natural Outcome Skin Care - Ultra Impact Marine Collagen Peptides Serum for Face - Facial Moisturizer Anti Aging Serum Gel for Firming, Lifting and Reducing Wrinkles, 1 oz

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Natural Outcome Mandelic Acid 10% | Anti-Aging AHA Facial Serum with Hyaluronic Acid | Targets Fine Lines, Dark Spots, and Wrinkles | Clarifies Acne and Stimulates Natural Collagen Production | 1 Oz

Natural Outcome Mandelic Acid 10% | Anti-Aging AHA Facial Serum with Hyaluronic Acid | Targets Fine Lines, Dark Spots, and Wrinkles | Clarifies Acne and Stimulates Natural Collagen Production | 1 Oz

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Pacifica Face Oil Serum - Flower Fix Bi-Phase Hydrating Skin Barrier - w/Hyaluronic Acid & Natural Botanical Ingredients - for Dry Sensitive Skin Vegan & Cruelty-Free Dermatologist Approved

Pacifica Face Oil Serum - Flower Fix Bi-Phase Hydrating Skin Barrier - w/Hyaluronic Acid & Natural Botanical Ingredients - for Dry Sensitive Skin Vegan & Cruelty-Free Dermatologist Approved

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Baebody Snail Mucin Serum Moisturizer - Hydrating Serum for Face with Collagen - Snail Mucin Moisturizer for Youthful Skin

Baebody Snail Mucin Serum Moisturizer - Hydrating Serum for Face with Collagen - Snail Mucin Moisturizer for Youthful Skin

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97% Snail Mucin Serum, Star Light by Zen Dew| Non-Sticky Snail Serum to Smooth, Brighten, Hydrate, Skin Repair |Cruelty Free, Made in S. Korea, 3.38 Fl Oz

97% Snail Mucin Serum, Star Light by Zen Dew| Non-Sticky Snail Serum to Smooth, Brighten, Hydrate, Skin Repair |Cruelty Free, Made in S. Korea, 3.38 Fl Oz

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