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Cold Medicines

10 Best Cold Medicines 2025 in the United States

Name: Zicam Cold Remedy Zinc Rapidmelts, Citrus Flavor, 25 Count (Pack of 1)
Brand: Zicam
Price: 10.98 USD
Availability: InStock

From leading brands and best sellers available on the web.

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

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Winner

Zicam

Zicam Cold Remedy Zinc Rapidmelts, Citrus Flavor, 25 Count (Pack of 1)

9.8

score

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Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

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Tylenol

Tylenol Cold + Flu Severe Medicine Caplets for Fever, Pain, Cough & Congestion, 24 ct.

9.6

score

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Vicks

Vicks DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, & Cough, 48ct

9.4

score

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Mucinex

Mucinex 12 Hour Maximum Strength 1200 mg Guaifenesin Extended-Release Tablets for Excess Mucus Relief, Expectorant Aids Excess Mucus Removal, Chest Congestion Relief, 42 Tablets

9.1

score

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Vicks

Vicks NyQuil SEVERE Cold, Flu, and Congestion Medicine, 2x12 fl oz Twin Pack, Berry Flavor, Maximum Strength, Nighttime Relief

8.8

score

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Zicam

Zicam Cold Remedy Cold Shortening Medicated Nasal Swabs Zinc-Free 20ct

8.5

score

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Sudafed

Sudafed PE Sinus Pressure + Pain Relief Tablets, Maximum Strength, Non-Drowsy, Acetaminophen, Pain Reliever, Fever Reducer, Phenylephrine HCl, Decongestant, Sinus Congestion Relief; 24 ct; Pack of 1

8.3

score

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Vicks

Vicks DayQuil & NyQuil Co-Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime & Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, & Cough, 72ct

8.0

score

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Amazon Basic Care

Amazon Basic Care Nighttime Severe Cold and Flu Syrup, Max Strength Liquid Medicine, Multi-Symptom Relief, for Adults and Children 12 Years and Older, Mixed Berry Flavor, 12 fl oz (Pack of 1)

7.7

score

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#10

Zicam

Zicam Cold Remedy No-Drip Nasal Spray with Cooling Menthol & Eucalyptus, Homeopathic, Zinc-Free, Pre-Cold Medicine, Shortens Cold Duration, 0.5 Ounce

7.4

score

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More products we considered

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

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Herbion Naturals Cough Drops - Honey Lemon Flavor, Soothing Dietary Supplement for Adults & Children (6+), 18 Drops, No Artificial Flavors or Colors

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HealthA2Z® Daytime and Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (24 Daytime & 12 Nighttime Softgels) (Daytime & Nighttime Combo (36 Count Pack of 1))

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HealthA2Z® Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (20 Softgels) (20 Softgels)

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HealthA2Z® Daytime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime(20 Softgels) (Daytime Cold & Flu Medicine (20 Count Pack of 1))

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10 Best Cold Medicines 2025 in the United States

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

Zicam Cold Remedy Zinc Rapidmelts, Citrus Flavor, 25 Count (Pack of 1)

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

Tylenol Cold + Flu Severe Medicine Caplets for Fever, Pain, Cough & Congestion, 24 ct.

Vicks DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, & Cough, 48ct

Mucinex 12 Hour Maximum Strength 1200 mg Guaifenesin Extended-Release Tablets for Excess Mucus Relief, Expectorant Aids Excess Mucus Removal, Chest Congestion Relief, 42 Tablets

Vicks NyQuil SEVERE Cold, Flu, and Congestion Medicine, 2x12 fl oz Twin Pack, Berry Flavor, Maximum Strength, Nighttime Relief

Zicam Cold Remedy Cold Shortening Medicated Nasal Swabs Zinc-Free 20ct

Sudafed PE Sinus Pressure + Pain Relief Tablets, Maximum Strength, Non-Drowsy, Acetaminophen, Pain Reliever, Fever Reducer, Phenylephrine HCl, Decongestant, Sinus Congestion Relief; 24 ct; Pack of 1

Vicks DayQuil & NyQuil Co-Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime & Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, & Cough, 72ct

Amazon Basic Care Nighttime Severe Cold and Flu Syrup, Max Strength Liquid Medicine, Multi-Symptom Relief, for Adults and Children 12 Years and Older, Mixed Berry Flavor, 12 fl oz (Pack of 1)

Zicam Cold Remedy No-Drip Nasal Spray with Cooling Menthol & Eucalyptus, Homeopathic, Zinc-Free, Pre-Cold Medicine, Shortens Cold Duration, 0.5 Ounce

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

Herbion Naturals Cough Drops - Honey Lemon Flavor, Soothing Dietary Supplement for Adults & Children (6+), 18 Drops, No Artificial Flavors or Colors

HealthA2Z® Daytime and Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (24 Daytime & 12 Nighttime Softgels) (Daytime & Nighttime Combo (36 Count Pack of 1))

HealthA2Z® Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (20 Softgels) (20 Softgels)

HealthA2Z® Daytime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime(20 Softgels) (Daytime Cold & Flu Medicine (20 Count Pack of 1))

FAQ

What is the best over-the-counter cold medicine?

What cold medicine is safe for children?

What are the best natural remedies for a cold?

Can you take cold medicine while pregnant?

What are the side effects of common cold medicines?

10 Best Cold Medicines 2025 in the United States

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

Zicam Cold Remedy Zinc Rapidmelts, Citrus Flavor, 25 Count (Pack of 1)

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

Tylenol Cold + Flu Severe Medicine Caplets for Fever, Pain, Cough & Congestion, 24 ct.

Vicks DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, & Cough, 48ct

Mucinex 12 Hour Maximum Strength 1200 mg Guaifenesin Extended-Release Tablets for Excess Mucus Relief, Expectorant Aids Excess Mucus Removal, Chest Congestion Relief, 42 Tablets

Vicks NyQuil SEVERE Cold, Flu, and Congestion Medicine, 2x12 fl oz Twin Pack, Berry Flavor, Maximum Strength, Nighttime Relief

Hyland's - Kids - Organic Cough & Immune Day & Night Combo Pack - Eases Coughs, Supports Immunity, Promotes Sleep, Two 4 Fl Oz. Bottles (8 fl oz) (Pack of 2)

Hyland's Naturals Baby Mucus and Cold Relief, Daytime Baby Cold Medicine, Infant Cold and Cough Remedy, Decongestant, 4 Fluid Ounce (Pack of 2)

Hyland's Baby Organic Cough & Immune Day & Night Combo Pack, Eases Coughs, Supports Immunity, Promotes Sleep + Chest Rub, Soothe & Comfort Organic Lavender, Peppermint, & Chamomile Flower Oil

Herbion Naturals Respiratory Care Herbal Granules with Natural Lemon Flavor–10 Ct, for The Whole Family –Healthy Respiratory Function-Relieves Cough

Herbion Naturals Respiratory Care Herbal Granules – 10 Ct for The Whole Family – Promotes Healthy Nasal Passages & Respiratory Function - Relieves Cold and Flu Symptoms – Supports Immune System

Zicam Cold Remedy Cold Shortening Medicated Nasal Swabs Zinc-Free 20ct

Sudafed PE Sinus Pressure + Pain Relief Tablets, Maximum Strength, Non-Drowsy, Acetaminophen, Pain Reliever, Fever Reducer, Phenylephrine HCl, Decongestant, Sinus Congestion Relief; 24 ct; Pack of 1

Vicks DayQuil & NyQuil Co-Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime & Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, & Cough, 72ct

Amazon Basic Care Nighttime Severe Cold and Flu Syrup, Max Strength Liquid Medicine, Multi-Symptom Relief, for Adults and Children 12 Years and Older, Mixed Berry Flavor, 12 fl oz (Pack of 1)

Zicam Cold Remedy No-Drip Nasal Spray with Cooling Menthol & Eucalyptus, Homeopathic, Zinc-Free, Pre-Cold Medicine, Shortens Cold Duration, 0.5 Ounce

Cold Medicine Otc

Cold And Flu Medicines

Cold Flu Medicines

Daytime Cold Medicines

Medicines Colds

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

Herbion Naturals Cough Drops - Honey Lemon Flavor, Soothing Dietary Supplement for Adults & Children (6+), 18 Drops, No Artificial Flavors or Colors

HealthA2Z® Daytime and Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (24 Daytime & 12 Nighttime Softgels) (Daytime & Nighttime Combo (36 Count Pack of 1))

HealthA2Z® Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (20 Softgels) (20 Softgels)

HealthA2Z® Daytime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime(20 Softgels) (Daytime Cold & Flu Medicine (20 Count Pack of 1))

FAQ

What is the best over-the-counter cold medicine?

What cold medicine is safe for children?

What are the best natural remedies for a cold?

Can you take cold medicine while pregnant?

What are the side effects of common cold medicines?