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Medicines Colds

10 Best Medicines Colds 2025 in the United States

Name: Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count
Brand: Tylenol
Price: 8.99 USD
Availability: InStock

From leading brands and best sellers available on the web.

Hyland's - Kids - Organic Cough & Immune Day & Night Combo Pack - Eases Coughs, Supports Immunity, Promotes Sleep, Two 4 Fl Oz. Bottles (8 fl oz) (Pack of 2)

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Winner

Tylenol

Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count

10.0

score

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Hyland's - Kids - Organic Cough & Immune Day & Night Combo Pack - Eases Coughs, Supports Immunity, Promotes Sleep, Two 4 Fl Oz. Bottles (8 fl oz) (Pack of 2)

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Zicam

Zicam Cold Remedy Zinc RapidMelts, Elderberry Citrus Flavor, Homeopathic, Cold Shortening Medicine, Shortens Cold Duration, 25 Count

10.0

score

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Zicam

Zicam Cold Remedy Cold Shortening Medicated Nasal Swabs Zinc-Free 20ct

9.9

score

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Vicks

Vicks DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, & Cough, 48ct

9.8

score

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Sudafed

Sudafed PE Sinus Pressure + Pain Relief Tablets, Maximum Strength, Non-Drowsy, Acetaminophen, Pain Reliever, Fever Reducer, Phenylephrine HCl, Decongestant, Sinus Congestion Relief; 24 ct; Pack of 1

9.7

score

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Amazon Basic Care

Amazon Basic Care Nighttime Severe Cold and Flu Syrup, Max Strength Liquid Medicine, Multi-Symptom Relief, for Adults and Children 12 Years and Older, Mixed Berry Flavor, 12 fl oz (Pack of 1)

9.5

score

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Mucinex

Mucinex Fast-Max Cold and Flu & Nightshift Severe Cold and Flu Medicine for Adults, Over-the-Counter Medication Combo Pack for Sore Throat Relief, Decongestant, Cough & Cold Medicines, 2 x 6 Fl Oz

9.4

score

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Mucinex

Mucinex Fast-Max Day Cold and Flu & Night Cold and Flu Medicine for Adults, Day/Night Combo Pack for Fever, Sore Throat Relief, Decongestant, Cough & Cold Medicines, 24 Fast-Dissolving Liquid Gels

9.2

score

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Boiron

Boiron ColdCalm Tablets for Relief of Common Cold Symptoms Such as Sneezing, Runny Nose, Sore Throat, and Nasal Congestion - Non-Drowsy - 60 Count

9.0

score

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#10

Hyland's

Editor’s Choice

Hyland's Kids Cough Syrup & Mucus Relief Daytime & Nighttime Combo Pack, Kids Cough Medicine for Ages 2-12, Grape Flavor, Natural Sleep Aid, Cough, Runny Nose, Mucus & Congestion, 8 Ounces

8.8

score

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More products we considered

HealthA2Z® Daytime and Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (24 Daytime & 12 Nighttime Softgels) (Daytime & Nighttime Combo (36 Count Pack of 1))

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Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

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HealthA2Z® Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (20 Softgels) (20 Softgels)

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HealthA2Z® Daytime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime(20 Softgels) (Daytime Cold & Flu Medicine (20 Count Pack of 1))

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HealthA2Z® Mucus Relief | Guaifenesin 400mg | Immediate Release | No Benzene | Expectorant (150 Counts)

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How do we rank products for you?

Our technology thoroughly searches through the online shopping world, reviewing hundreds of sites. We then process and analyze this information, updating in real-time to bring you the latest top-rated products. This way, you always get the best and most current options available.

10 Best Medicines Colds 2025 in the United States

Hyland's - Kids - Organic Cough & Immune Day & Night Combo Pack - Eases Coughs, Supports Immunity, Promotes Sleep, Two 4 Fl Oz. Bottles (8 fl oz) (Pack of 2)

Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count

Hyland's - Kids - Organic Cough & Immune Day & Night Combo Pack - Eases Coughs, Supports Immunity, Promotes Sleep, Two 4 Fl Oz. Bottles (8 fl oz) (Pack of 2)

Zicam Cold Remedy Zinc RapidMelts, Elderberry Citrus Flavor, Homeopathic, Cold Shortening Medicine, Shortens Cold Duration, 25 Count

Zicam Cold Remedy Cold Shortening Medicated Nasal Swabs Zinc-Free 20ct

Vicks DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, & Cough, 48ct

Sudafed PE Sinus Pressure + Pain Relief Tablets, Maximum Strength, Non-Drowsy, Acetaminophen, Pain Reliever, Fever Reducer, Phenylephrine HCl, Decongestant, Sinus Congestion Relief; 24 ct; Pack of 1

Hyland's Kids Nighttime Organic Cough Syrup & Immune Support with Agave, Elderberry & Pomegranate - Soothes Cough and Cold, & Supports Immunity - 4 Fl. Oz.

Herbion Naturals Respiratory Care Herbal Granules – 10 Ct for The Whole Family – Promotes Healthy Nasal Passages & Respiratory Function - Relieves Cold and Flu Symptoms – Supports Immune System

HealthA2Z® Mucus Relief DM | Dextromethorphan HBr 20mg | Guaifenesin 400mg | No Benzene | Cough, Immediate Release, Uncoated (120 Count (Pack of 1))

HealthA2Z® Mucus Relief | Guaifenesin 600 mg | 12 Hour | No Benzene | Expectorant | Relieves Chest Congestion | Thins and Loosens Mucus | Extended Release (150 Counts)

HealthA2Z® Mucus Relief | Guaifenesin 1200 mg | NO Benzene |100 Tablets | Maximum Strength | 12 Hour | Expectorant | Relieves Chest Congestion | Thins and Loosens Mucus

Amazon Basic Care Nighttime Severe Cold and Flu Syrup, Max Strength Liquid Medicine, Multi-Symptom Relief, for Adults and Children 12 Years and Older, Mixed Berry Flavor, 12 fl oz (Pack of 1)

Mucinex Fast-Max Cold and Flu & Nightshift Severe Cold and Flu Medicine for Adults, Over-the-Counter Medication Combo Pack for Sore Throat Relief, Decongestant, Cough & Cold Medicines, 2 x 6 Fl Oz

Mucinex Fast-Max Day Cold and Flu & Night Cold and Flu Medicine for Adults, Day/Night Combo Pack for Fever, Sore Throat Relief, Decongestant, Cough & Cold Medicines, 24 Fast-Dissolving Liquid Gels

Boiron ColdCalm Tablets for Relief of Common Cold Symptoms Such as Sneezing, Runny Nose, Sore Throat, and Nasal Congestion - Non-Drowsy - 60 Count

Hyland's Kids Cough Syrup & Mucus Relief Daytime & Nighttime Combo Pack, Kids Cough Medicine for Ages 2-12, Grape Flavor, Natural Sleep Aid, Cough, Runny Nose, Mucus & Congestion, 8 Ounces

Cough Medicines

Cold And Flu Medicines

Cold Flu Medicines

HealthA2Z® Daytime and Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (24 Daytime & 12 Nighttime Softgels) (Daytime & Nighttime Combo (36 Count Pack of 1))

Safrel Pharma Mucus Relief Guaifenesin 400 mg - Fast Acting Expectorant, Thins and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (500 Count (Pack of 1))

HealthA2Z® Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (20 Softgels) (20 Softgels)

HealthA2Z® Daytime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime(20 Softgels) (Daytime Cold & Flu Medicine (20 Count Pack of 1))

HealthA2Z® Mucus Relief | Guaifenesin 400mg | Immediate Release | No Benzene | Expectorant (150 Counts)